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Authentic Biochemistry
Authentic Biochemistry episodes
- Biochemical Mosaic II.c.7. Fatty acid desaturation and mole% PC/PE/PL/CER are elevated via circRNA in Medublastoma while AGPS increased circRNA's in thyroid cancer.DJGPhD.7Mar24. Authentic Biochem.
References
Acta Neuropathologica Communications 2023. volume 11, Article number: 38
Proc Natl Acad Sci U S A. 2020 Apr 7; 117(14): 7792–7798
Front Mol Biosci. 2022; 9: 925389.
Front Cell Dev Biol. 2021; 9: 636838
Oncol Lett 2018. 15: 7889-7899.
Saint-Saëns, C. 1886. Symphony No 3 in C minor, Op 78
https://youtu.be/ZWCZq33BrOo?si=8hQ01E9jfp0eU07o
Winwood,S. 1969. Had to Cry Today (Blind Faith)
https://youtu.be/Z4Yo_VbGdMg?si=tWz0_qnG5Nsx5qxX
30 min - Biochemical Mosaic II.c.6 Meduloblastoma is linked to plasmalogen and circ RNA phenomena that are pathophenocopied in other cancers. DJGPhD.5.Mar24.Authentic Biochemistry
References
Acta Neuropathologica Communications 2023. volume 11, Article number: 38
Proc Natl Acad Sci U S A. 2020 Apr 7; 117(14): 7792–7798.
Int J Med Sci. 2022; 19(6): 975–985
Nature Communications 2022. volume 13, Article number: 1508
Lassus. O. 1578. Requiem - Missa pro defunctis (4vv) : Offertorium
https://youtu.be/UXY4hxCvu7M?si=lcM_lw11lbPWrYX4
30 min - Biochemical Mosaic II. c.5 Peroxisomal plasmalogen biosynthesis may regulate transcriptomic and proteomic sequalae to plasmamembrane mediated signal transduction. DJGPhD.4March24.
References
Front Physiol. 2021; 12: 730829.
Non-coding RNA Investig 2017. 1:5.
Genome Biology 2011. volume 12, Article number: 236
RNA Biol . 2021 Nov 12;18(sup2):574-585.
Hunter. R. 1975. "Cruel White Water"
https://youtu.be/T-oBD3F74Nk?si=zsrEBN0JKan_FXdH
30 min - Biochemical Mosaic II. c.4. Peroxisomal biogenesis and AGPS-mediated plasmalogen synthesis involve circular RNA species that alter microRNA and mRNA expression in human cancers. DJGPhD.3MAR24.
References
Genome Res. 2004 Nov;14(11): 2245–2252.
Int J Med Sci. 2022; 19(6): 975–985.
Oncol Lett. 2018 May; 15(5): 7889–7899.
Cell Death Dis. 2020 Dec; 11(12): 1065.
RNA Biol . 2021 Nov 12;18(sup2):574-585
Bach, J Christian. 1775. Sinfonie Concertante
https://youtu.be/S8NPgouJ5uk?si=_azSWNelNFRA2ai5
30 min - Saturday Night Authentic Biochemistry The Agentic operator as metaphysical metaphor in metabolic regulation. DJGPhD.2March 2024.
References
Dr Guerra Archives: Graduate Biochemistry Lecture notes and syntheses
Simon, P. 1969. The Boxer.
https://youtu.be/l3LFML_pxlY?si=Nv5-mSzRu6fHP8Sr
Boccherini, L. 1760. 7. Cellokonzert
https://youtu.be/NSU6Ylxaobs?si=PZW0S3mWl25RwnE2
30 min - Biochemical Mosaic II. c.3 Plasmalogen metabolism is coherently associated with peroxisomal integrity and replication. DJGPhD.01March 2024 Authentic Biochemistry.
References
Oncol Lett. 2018 May; 15(5): 7889–7899
Nat Genet. 1997 Apr;15(4):369-76
Biochim Biophys Acta Mol Cell Res. 2020 Feb;1867(2):118609
Protein Cell 2018. 9, 196–206
Brain Research Bulletin 2023. 194: 118–123
The Moody Blues. 1968. "In Search of the Lost Chord"
https://youtu.be/k5UdP-SFNgY?si=zDboUgA2LDi3E7m1
30 min - Biochemical Mosaic II. C.2. Plasmalogen and PAF biosynthesis in relation to glycerol lipid and intermediary subcellular metabolism.DJGPhD.27.2.24
References
Guerra: graduate biochemistry lectures
Chopin, F. 1830. Nocturne E Flat Major Op.9 No.2
https://youtu.be/tV5U8kVYS88?si=MKxfguVRI6hhQeMO
Winwood, Wood and Capaldi 1967. Dear Mr Fantasy. Traffic.
https://youtu.be/sS_eHdqcrM8?si=95X9RWJD2Q4w456S
30 min - Biochemical Mosaic II. Plasmalogens & other ether lipids. c.1 DJGPhD.26.2.24. Authentic Biochemistry Podcast
References
Cell Metab. 2014 Mar 4; 19(3): 380–392.
Protein Cell 2018. 9, 196–206.
Membranes 2023, 13(9), 764.
Debussy , C. (. 1890;1905) Clair de lune.
https://youtu.be/6zzWnxuQPWI?si=gcEAKpbgc9xO8esf
Morricone. E. 1968. "Once Upon a Time in the West"
https://youtu.be/j5eQ9UTmDLo?si=-eUjJ1s9hAd6fpwz
Schubert, F. 1825. Ave Maria
https://youtu.be/2H5rusicEnc?si=LcYisCODwtGgjjVx
30 min - A Dialectical Interlocution with Mozart. DJGPhD.24.2.24 Authentic Biochemistry Podcast
References
Mozart.WA
1782. Fantasie in D minor. K.397
https://youtu.be/OYiz_u0tDwM?si=0dP736rTEkb4sauL
1785.Piano Concerto 22 in E flat Major.K.482
https://youtu.be/EJYPnrYNt8A?si=VqgS-PNw2bnbIFBj
1788.Divertimento in E♭ major, K. 563.
https://youtu.be/2N4hHhTu4pw?si=p-VwHTTOK5ixFWfk
1787. Eine kleine Nachtmusik, K. 525.
https://youtu.be/156u4nV2uGE?si=bRqysFpbi-6j0jMk
29 min - Biochemical Mosaic I. CODA. Membrane lipids function as biosensors for pKa's of phosphonoester anionic charge density with polybasic protein domains to mediate communication including transcription.
References
J Biol Chem 2017 292: 20481.
Nature Cell Biology 2019. volume 21, pages 338–347
Rossini.G. 1829. William Tell Overture.
https://youtu.be/z7Tj2SzToHI?si=QUXkj3NzqF17Zq60
Vivaldi, A. 1712. Concerto in D Major. RV 212.
https://youtu.be/l21_9KKy1Pg?si=9HSMxRj7huJF1B8j
30 min
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You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.