Sign up to save your podcasts
Or
Share Authentic Biochemistry
Share to email
Share to Facebook
Share to X
Share to email
Share to Facebook
Share to X
Or
Authentic Biochemistry
Authentic Biochemistry episodes
- Biochemical MosaicI.c.13 Phosphatidic acid as key lipid intermediary of membrane secretion signalling and cellular intracommunication via kinase cascade and transcriptional regulation.DJGPhD.22.2.24
References
Biomedicines 2023, 11(7), 1804
BMC Biology. 2011. 9:85
Cancer Res. 2011 Jan 15;71(2):293-7.
FEBS Lett.2019.593.17:2428-2451
Verdi, G. 1841. Nabucco Overture
https://youtu.be/OseGETWEnCo?si=LhiIQV-N0-_Z_s-s
Lennon&McCartney. 1966 "For No One". Beatles: Revolver.
https://youtu.be/sep5E3ssXLQ?si=WLtMrP-Xq279qZXl
30 min - Biochemical Mosaic I. c.12. The porosomal secretory system requires anioic lipids including phosphatidic acid. DJGPhD.21.2.24
Dr. Guerra: membrane graduate biochemistry lecture notes
J Cell Mol Med . 2015 Jul;19(7):1427-40
Langmuir, 2018, 34 (1), pp 530–539
Elgar, E. 1900. The Dream of Gerontius
https://youtu.be/rnwmVypRY-g?si=CxF8tZrfRR-uWdhn
30 min - Biochemical Mosaic I.c.11. Glycerolipid metabolism coupled to mTORC1 enzyme phosphorylation necessarily involves a complete analysis of membrane lipid molecular species distribution.DJGPhD.20.2.24
References
Nature . 2019 Nov;575(7782):361-365.
Adv Biol Regul. 2017 May:64:39-48
J Biol Chem. 2013 Apr 5; 288(14): 9933–9945
Redox Biology.2017. Volume 11, April. Pages 622-630
Biochim Biophys Acta. 2011 Jun;1811(6):377-85
Dr Guerra: lipid lectures archives
Schubert, F. 1816. Symphony #5
https://youtu.be/OHkot1TmvZU?si=uYtQfxUegl3KrkRK
Newman, L Darby K. 1954. Marilyn Monroe. The River of No Return
https://youtu.be/dLzeHkEQe9g?si=nXMd20gstc3vVdgl
30 min - Biochemical Mosaic I c.10. Is PE depletion reversed by mTORC1 phosphorylation of LIPIN1 or is DAG authentically activating CCT via membrane association thus obtaining robust PL synthesis? DJGPhD.
References
Biochim Biophys Acta. 2011 Jun;1811(6):377-85
Am J Physiol Lung Cell Mol Physiol 2001. 281: L98–L107.
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism 1997. Volume 1348, Issues 1–2, 4 Pages 79-90.
Am J Physiol Lung Cell Mol Physiol 2001. Volume 281. Issue 1July Pages L108-L118
JBC 1991. Volume 266, Issue 36, 25 December. Pages 24503-24508
Progress in Lipid Research. 2015. Volume 59, ages 147-171
Nature 2019. volume 575, pages 361–365
30 min - Biochemical Mosaic I. c.9 Increased inner mitochondrial membrane PE from PS decarboxylase decreases protease mediated degradation of phospholipid transfer proteins thus maintaining fusion potency.
References
PLoS Biol 2014. 12(10): e1001969
J Biol Chem. 2012 May18;287(21):17589-17597
J Biol Chem. 2012 Nov 23;287(48):40131-9
Nature 2019. volume 575, pages 361–365
Alleluia: Lobet den Herren.30 min - Biochemical Mosaic I PA-phosphatase c.8. Membrane fusion and the dynamics of mitochondrial reduction vs. proliferation; the PA phosphatase in lipid metabolism. DJGPhD. 16.2.24 Authentic Biochemistry
References
Dr Guerra membrane lectures archive
FASEB J. 2021 Jun; 35(6): e21620.
Vivaldi, A. 1711. Concerto for 4 Violins in B minor RV 580
https://youtu.be/SY3Kxf7ZTeI?si=JLQXMtK06Y6Yfu_k
30 min - Biochemical Mosaic I. Phosphatidic acid Phosphatase. c.7. Mutational reversal of IDH1 leads to NADPH depletion concomitant with potent anti-PHD enantiomeric 2-hydroxyglutarate obtaining pseudohypoxia.
References
FEMS Microbiol Rev.1998. Oct;22(4):255-75Discoveries(Craiova). 2017 Jul-Sep; 5(3): e77.
J Cell Mol Med. 2015 Jul; 19(7): 1427–1440.
Oncogene. 2017 Mar 23; 36(12): 1607–1618.
Bach, JS. 1742. Kunst der Fuge , BWV 1080; Marta Czech
https://youtu.be/p1Sq1HOYglU?si=2GMF7kf3dLW4rr2O
Lennon and MCartney.1968. "Martha my Dear"
https://youtu.be/RXawa90YU2s?si=dUPDtTdm4UqrgWit
30 min - Biochemical Mosaic I. The PA phosphatase c.6. Alteration of the TCA pathway intermediates and hypoxia/nutrient deficiency control HIF1α stability indirectly regulating IMM protein and lipid turnover.
References
Front. Oncol. 2017. 26 November.V.7.
Oncogene. 2017 Mar 23; 36(12): 1607–1618.
Schubert, F. 1819 Piano Quintet in A major, D. 667/ "Trout"
https://youtu.be/syod5rkFdNY?si=5F3rexiou7dTifYg
Hunter, R., Garcia , J. 1970 "Ripple"
https://youtu.be/xofhZx9eWUQ?si=tpOAMzyW5qUy01P_
30 min - The Biochemical Mosaic I. Phosphatidic Acid Phosphatase c.5. Tumor cells adapt bioenergetic fuel economy toward cell immortalization via re-crafting of mitochondrial IM lipid speciation.DJGPhD.12Feb24
References
Cell Metabolism 2019. 30: 720–734
Nature 2019. 575: 361–365
Squire, C. 1978. "Onward" Yes.
30 min - Biochemical Mosaic I. Phosphatidic Acid Phosphatase c.4 GLN utilization and an IMM protease regulate mitochondrial involvement in cancer growth. DJGPhD. Authentic Biochemistry 10Feb24
References
Cell Death & Disease 2022. volume 13.Article number: 444.
Nature 2019. volume 575, pages 361–365
Scientific Reports 2021. volume 11, Article number: 16512
Experimental & Molecular Medicine 2020. volume 52, pages 1496–1516
Mozart, WA. 1788. Piano Trio in G Major, KV 564
https://youtu.be/oOEuVtr8sF0?si=3-9RK1XkGkSWne7I
30 min
About Authentic Biochemistry
From the publisher's feed
Become a Paid Subscriber: https://anchor.fm/dr-daniel-j-guerra/subscribe
Become a Paid Subscriber: https://anchor.fm/dr-daniel-j-guerra/subscribe
You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.