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Authentic Biochemistry
Authentic Biochemistry episodes
- Holiday Ethanol Use VI. EtOH associated DNA methylation of neurotransmitter systems opens the door to neurotoxicity and cognitive deficits. DJGPhD.18.12.22b. Authentic Biochemistry Podcast
References
Dr Guerra EtOH lectures
Dr Guerra Reward Pathway lectures
Biol Psychiatry. 2020 Jan 1; 87(1): 64–73
Biochemistry and Cell Biology. 2019. Volume 97, Number 4.August.
30 min - Holiday Ethanol Use V. EtOH mediated WNT signaling and PLC mediated IP3/DAG induction of protein kinase and Ca2+ mobilization contribute to aberrant transcription and translation corrupting health.
References
Dr Guerra EtOH lectures
Physiol Rev 2016. 96: 1261–1296.
Clinical and Molecular Teratology. 2016. Volume 106, Issue 9 Pages 749–760
30 min - Holiday Ethanol Use IV. MDH and LDH play essential roles in EtOH mediated corruption of bioenergetics, development, and gene expression during fetal development.DJGPhD.16.12.22 b.Authentic Biochem.
References
Dr Guerra's EtOH lectures
Cells. 2020 Sep; 9(9): 2125.
30 min - Holiday Ethanol Use III. In utero fetal cardiac muscle development is corrupted by maternal EtOH exposure via metabolic, bioenergetic and epigenetic means involving fatty acid and folate redox poise.
References
Dr. Guerra's EtOH lectures
Clinical and Molecular Teratology 2016. Volume 106:749–760
Stat Pearls. Embryology and Gastrulation. NIH 2022. https://www.ncbi.nlm.nih.gov/books/NBK554394/
30 min - Holiday EtOH Lecture II. Ethanol ingestion permanantly corrupts myelin lipid composition while altering MET and Folate metabolism leading to epigenetic syntactic and semantic chromatin errors.DJGPhD.
References
Clinical and Molecular Teratology Volume 106, Issue 9 September 2016 Pages 749–760
Alcohol, 2017-12-01, Volume 65, Pages 51-62
30 min - Immunoepigenetics VII. MicroRNA mediated feedback control over signalling response toward inflammation.DJGPhD. 10Dec22. Authentic Biochemistry
References
Arthritis Res Ther. 2021; 23: 19.
Frontiers in Immunology. November 2014. 21(578):1
30 min - ImmunoepigeneticsV!. TLR's and TCR's use membrane lipid raft signal transduction to obtain transcription factor mediated cell fate via epigenetic modification. DJGPhD.09 Dec.22
References
Frontiers in Immunology November 2014. 21(578):1
Clin Epigenetics. 2017; 9: 94
Cancer Cell International September 2020. 20(1):429
30 min - ImmunoepigeneticsV. TCR activation and the integration of cell senescence with epigenetic authorship and reading-mediated tumorigenesis. DJGPhD.07Dec22. Authentic Biochemistry
References
Cancer Cell Int. 2022; 22: 272.
Cell Mol Life Sci. 2013 Oct;70(20):3753-72
PLoS Biol. 2013 Mar; 11(3): e1001502
30 min - ImmunoEpigeneticsIV. Membrane lipid raft components dynamically mediate Tcell reception, hippocampal pyrimidal neuron endocytosis, and lung cancer cell mesenchymal to endothelial transition.DJGPhD.
References
Respir Res. 2017 Sep 6;18(1):168
Front Behav Neurosci. 2020; 14: 24
JLR Methods| 2020.Volume 61, ISSUE 11, P1512-1523, November 01
30 min - Immunoepigenetics 3. EtOH abuse interrupts membrane lipid raft -mediated TCR signaling by decreasing the TF NFAT nuclear translocation and IL-2 transcription.DJGPhD.04.DEC.22.Authentic Biochemistry.
Reference
Alcohol Clin Exp Res. 2011 Aug; 35(8): 1435–1444
30 min
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You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.