Authentic Biochemistry

By Dr Daniel J. Guerra

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FAQs about Authentic Biochemistry:

How many episodes does Authentic Biochemistry have?

The podcast currently has 1,183 episodes available.

Authentic Biochemistry episodes:

December 23, 2021 AMPK negatively regulates lipogenesis by phosphorylating ACCase 1&2 plus HMGCoA reductase thus supporting beta oxidation of fatty acids . Dr. Daniel J. Guerra. 22.12.21. Authentic Biochemistry
Cell Metabolism 2020 31472-492
Amino Acids. 2012 Oct;43(4):1803-7
Molecular Cell Volume 81, Issue 18, 16 September 2021, Pages 3677-3690
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30min
December 21, 2021 AMPK is associated with the POMC vs, NPY neuronal axis under Leptin Control. DJGPhD. 20.12.21 Authentic Biochemistry
References
HORMONES 2013, 12(2):172-191
Proc Natl Acad Sci U S A . 2002 Dec 24;99(26):17155-60
Eur J Endocrinol. 2017 176(5): R235–R246.

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30min
December 20, 2021 AMPK Allosteric Regulation and Interaction with the Opposing mTORC Network. Part 2. Dr. Daniel J. Guerra. Authentic Biochemistry 19.12.21
Eur J Endocrinol. 2017 176(5): R235–R246
Molecular Cell Volume 81, Issue 18, 16 September 2021, Pages 3677-3690
...more
30min
December 19, 2021 Bio-Molecular Regulator Series . AMPK. Part One. Dr. Daniel J. Guerra. Authentic Biochemistry Podcast Production.19.12.21.
An introductory lecture on the biomolecular sensor kinase, Adenosyl Mono-Phosphate (protein) Kinase; AMPK.
References
Mol Genet Metab. 2013 Jul;109(3):260-8
PLoS One. 2016 Aug 16;11(8):e0161252.
Experimental & Molecular Medicine volume 48, 224 (2016)
Molecular Cell Volume 81, Issue 18, 16 September 2021, Pages 3677-3690
...more
30min
December 12, 2021 T-lymphocyte and macrophage membrane CD38 ecto-enzyme mediated NAD catabolism is associated with ageing and the decline in Sirtuin-mediated deacylase activity. DJGPhD.11.Dec.21' Authentic Biochemistry
References
Cell Metabolism. 2016. 23, 1127–1139
Cells 2020, 9(1), 228
Front. Immunol., 31 May 2019
Int J Mol Sci. 2020 Nov; 21(22): 8609
Circ Res. 2018 Sep 14; 123(7): 868–885.
Int J Mol Sci. 2019 Mar; 20(5): 1223
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30min
December 10, 2021 Synthesis of the sirtuin locus and NAD+ with T lymphocyte CD38 and the corruption over control on inflammation. DJGPhD. Authentic Biochemistry 10.Dec21. II
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Cells 2020, 9(1), 228
Circ Res. 2018 Sep 14; 123(7): 868–885
Front. Immunol., 31 May 2019

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30min
December 10, 2021 Aposteriori synthesis of neuroendocrine linked clock chronicity and the Senescent associated Secretory Phenotype through the synthetic apriori lens of NAD+. DJGPhD.10Dec21. Authentic Biochemistry
References
Nat Cell Biol. 2019 Mar; 21(3): 397–407
J Diabetes Metab Disord. 2020 Jul 21;19(2):1797-1825
Int. J. Mol. Sci. 2014, 15, 16848-16884
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30min
December 08, 2021 How testosterone-aromatase derived estradiol transformation to 2-methoxy-17beta-estradiol can mitigate cell proliferation by promoting a senescent phenotype.DJGPhD. Authentic Biochemistry.8.DEC.21
Besides 2-methoxy-17beta-estradiol, cell cycle arrest via chromatin deacetylation can mitigate cell proliferation by decreasing global transcription while promoting the expression of tumor suppressor genes like p16INK4a while DNA Damage Repair (DDR) from pro-inflammatory cytokine production from senescent cells and Th1 lymphocytes can inhibit commitment to mitosis and cytokinesis by generating the paracrine SASP paradigm.
Refs.
Am J Physiol Cell Physiol 2012;302:C1026-C1034
Steroids Volume 75, Issue 10, October 2010, Pages 625-631
Oncotarget. 2013 Oct; 4(10): 1552–1553
Cancer Metastasis Rev. 2020; 39(3): 681–709

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31min
December 07, 2021 Blocking cellular senescence may suppress autoimmune diseases and reactive oxygen mediated cell death but non-ironically promote oncogenesis and tumor development during ageing. DJGPhD. 06.DEC.21
Cell fate from Either ageing associated senescence to programmed cell death OR cell proliferation is finely tuned to the splice variant expression of Cell Cycle dependent kinase inhibitors and the relative production of pro-inflammatory cytokines under the synchrony of DNA Damage Repair (DDR), telomerase expression decline, and the protective role of the Senescence Associated Secretory Phenotype (SASP).
Dr. Daniel J. Guerra. 06 Dec 2021 Authentic Biochemistry Productions
References:
Oncotarget. 2013 Oct; 4(10): 1552–1553
Cancer Rep Rev. 2018 Mar; 2(2): 10
Nat Med. 2017 Jun; 23(6): 775–781
Cancer Genet Cytogenet. 1999 Mar;109(2):108-13.
EBioMedicine 2016 830-39DOI: (10.1016/j.ebiom.2016.04.017

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30min
November 25, 2021 Ageing and Asymmetric Dimethylarginine (ADMA)in Endothelial Nitric Oxide Synthase inhibition-associated decrease in respiratory vasodilation. Dr Dan Guerra 24.11.21 Authentic Biochemistry
Age Ageing, Volume 48, Issue 6, November 2019, Pages 776–782
Biomedicines. 2020 Aug 6;8(8):277

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30min

FAQs about Authentic Biochemistry:

How many episodes does Authentic Biochemistry have?

The podcast currently has 1,183 episodes available.