In 2012, the discovery of the gene-editing tool CRISPR-Cas9 revolutionised scientists’ ability to modify DNA. Ten years on, host Alok Jha speaks to Jennifer Doudna, the Nobel laureate who pioneered the technology. She explains how CRISPR could transform healthcare and the food supply—and help with the fight against climate change. Plus, how does she grapple with the ethical questions raised by the technology she helped to invent?

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