Chronic heartburn and GERD are often brushed off as everyday issues—but for some patients, long-term reflux can quietly progress to Barrett's esophagus, the only known precursor to esophageal cancer.

In Part 1 of this 4-part U.S.-focused patient education series, foregut surgeon Dr. Dan Lister, Founder of the Arkansas Heartburn Treatment Center, explains how reflux disease can evolve over time and why early recognition matters.

In this episode, you'll learn:

• How chronic GERD can progress silently

• Why Barrett's esophagus matters—even when symptoms improve or disappear

• Key warning signs patients should never ignore

• How Barrett's is detected and risk is assessed in the U.S.

• Treatment approaches that may help reduce cancer risk

Whether you've lived with reflux for years or are newly diagnosed, this episode provides clear, evidence-based guidance to help you take reflux seriously—and take action.

This episode is part of a 4-part patient education series sponsored by Castle Biosciences and produced in collaboration with leading U.S. clinicians dedicated to improving outcomes for patients with Barrett's esophagus.