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Basilar Artery Blockage. Bolus Breakthrough. Better Outcomes. 🧠💉📈
Can a single bolus change the fate of a devastating stroke? 🧠💉
The TRACE-5 trial (Lancet 2026) shows that tenecteplase within 24 h for basilar artery occlusion improves excellent functional outcomes (38% vs 29%; RR 1.50, p=0.014) without increased haemorrhage or mortality. 📊
Pragmatic design. No mandatory advanced imaging. Feasible globally. 🌍
If confirmed beyond Asian cohorts, this could reshape late-window stroke care.
Single shot. Shifted scale. Strong signal. 🚑📈
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By Dr RR Baliga, MD, MBA
5
66 ratings
Can a single bolus change the fate of a devastating stroke? 🧠💉
The TRACE-5 trial (Lancet 2026) shows that tenecteplase within 24 h for basilar artery occlusion improves excellent functional outcomes (38% vs 29%; RR 1.50, p=0.014) without increased haemorrhage or mortality. 📊
Pragmatic design. No mandatory advanced imaging. Feasible globally. 🌍
If confirmed beyond Asian cohorts, this could reshape late-window stroke care.
Single shot. Shifted scale. Strong signal. 🚑📈
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