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Your emotions do not reflect an irrefutable truth. Psychologist Kristen Lindquist explains how important that is for connecting across cultures.
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How a ‘heroic dose’ of psychedelics can be therapeutic, explained by a Johns Hopkins professor.
Chapters:
0:00 Effing up the ineffable
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Climate change. War. Civil unrest. Is it responsible to have kids today? Futurist Ari Wallach explains.
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Timestamps:
0:00 - Human life in modern times
0:25 - Gaining control over nature
1:58 - The productivity of agriculture
2:45 - Is our species evolving?
4:28 - Slow biological evolution
**🌍 From Survival to Supremacy: How We Took Charge of Nature**
Drop someone from the 1800s into today’s world and they’d probably think they’d landed on another planet 🚀.
From food to medicine, transport to tech, life has transformed at warp speed — all thanks to one major shift: **we’ve gained control over nature** 🧠⚙️🌿.
Once vulnerable to famine, disease, wild beasts, and drought…
We’ve now **erased smallpox**, tamed TB, and made rubella a forgotten word 💉.
Our understanding of biology has turned **invisible killers** into manageable annoyances.
We even grow more food than ever — with just **2% of the population farming** 👨🌾 — feeding not just nations but the world.
But here’s the twist:
**Cultural evolution is sprinting**, while **biological evolution is crawling** 🐌💨.
Our bodies are still wired for scarcity — craving fat, sugar, and salt like ancient hunter-gatherers —
while modern life gives us an **endless buffet** 🍩🥤🍟.
That mismatch? It’s causing modern syndromes our ancestors never dreamed of.
Now imagine if humanity had stayed scattered — isolated like species on separate islands.
We might have evolved into wildly different beings 🧬🌎.
But instead, thanks to travel and tech, we’re **sharing genes and culture at lightning speed** 🌐 — stalling deep biological change, but accelerating cultural shifts.
We’re now a **hyperconnected species** — blending traditions, ideas, even immune systems —
but still stuck with bodies that were built for a different world.
**✨ So what’s next?**
We’ve mastered nature.
But can we master ourselves?
About Sean B. Carroll:
Sean B. Carroll is an award-winning scientist, author, educator, and film producer. He is Distinguished University Professor and the Andrew and Mary Balo and NIcholas and Susan Simon Chair of Biology at the University of Maryland, and an Investigator of the Howard Hughes Medical Institute. He was formerly Head of HHMI Tangled Bank Studios, and led the Department of Science Education from 2010-2023. He is also Professor Emeritus of Genetics and Molecular Biology at the University of Wisconsin.
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Pressure bursts pipes. Keeping a secret can do the same to your mind, explains Michael Slepian.
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How did complex systems emerge from chaos? Physicist Sean Carroll explains.
Chapters for easier navigation:
0:00 Entropy: The 2nd law of thermodynamics
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"There will always be too much to do. You're never going to feel completely ready. You're never going to be able to feel confident about what's coming in the future."
Many of us wake up each morning with something Oliver Burkeman calls “productivity debt.” The bestselling author and journalist explains this term as “a sense that you've got to work really hard during the day to pay off this debt of getting things done. Otherwise, you won't quite feel like you're an adequate and acceptable human being.”It's becoming very obvious that this ever-accelerating treadmill of productivity isn't going to lead to a final, perfect destination. There will always be more to do. You're never going to feel completely ready. You're never going to be able to feel confident about what's coming in the future. If you set out on some big project of scheduling your time very, very, very strictly, not only will you probably fail and get very stressed, but even if you succeed, you'll fail in a way because there'll be some lack of spontaneity to that path, a sense of having to carry out these instructions that you've given yourself that is at odds with what we really value from being alive. And so that's why we need a way of understanding and thinking about work and productivity that does not treat getting on top of everything as the goal, explains Burkeman. Here, he lays out four guiding principles to lead a better, more fulfilling life.
In this episode, we explore the trap of perfectionism and the endless pursuit of productivity. The discussion challenges the idea that getting on top of everything will bring peace, revealing instead that true relief comes from accepting life's inherent limitations. Strategies like the 3-4 hour deep work rule, keeping a "done" list, and embracing spontaneity help shift the focus from control to meaningful progress. By letting go of the pressure to maximize every moment, we can create space for what truly matters.
About Oliver Burkeman:Oliver Burkeman is a bestselling author and journalist. He is best known for Four Thousand Weeks: Time Management for Mortals (2021), a self-help book on reframing productivity for happiness. He also publishes The Imperfectionist, an email on productivity, mortality, the power of limits, and building a meaningful life in an age of bewilderment.
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This interview is an episode from @The-Well, our publication about ideas that inspire a life well-lived, created with the @JohnTempletonFoundation.
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“Over the last 10 or 15 years, scientists have really started to understand the fundamental underlying biology of the aging process. And they broke this down into 12 hallmarks of aging.”
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**🌪️ From Chaos to Clarity: A Rockstar's Journey to Redemption 🎸🕊️**
Growing up on a tour bus with Ozzy Osbourne as your dad, "normal" was never in the cards. Fame hit hard when *The Osbournes* skyrocketed—and so did addiction. Jack Osbourne took his first drink at 14 and was snorting 400mg of Oxycontin with Jack Daniels not long after. The rush? Temporary. The loneliness? Crushing.
By 17, worn out, depressed, and on the brink, he entered rehab—not for a miracle, but for structure. Slowly, sobriety took hold. Chores, schedules, and reflection replaced the chaos. The turning point? Becoming a dad.
Now, Jack knows that version of himself still lives inside—but so does the strength to choose differently every day. 🌅
**“The Universe unfolds exactly as it should.”** And for Jack, that’s meant trading destruction for purpose—and loving every second of fatherhood. 💙
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