On this episode of Talking Buffalo, Patrick Moran has a full Buffalo Bills vs San Francisco 49ers preview of their upcoming prime time game on Sunday night in addition to some bold predictions and a final score guess.

Hope everyone enjoyed their Thanksgiving. Chances are everyone in the Bills organization did and with good reason---they're coming off a bye week with a 9-2 record and an opportunity to have the top overall seed in the AFC as we head down the stretch. Patrick spends a few minutes talking about what's gotten the Bills to the point, including being the best team in the NFL at taking the ball away compared to turning it over themselves. He also talks about the injuries, which besides Dalton Kincaid look incredibly promising for Sunday.

As for the 49ers, the defending NFC champs are underwhelming at just 5-6 and much like the Bills, have been hit very hard all season long by injuries. Patrick discusses that including a trio of key 49ers who are anything but a lock to be playing on Sunday night----Nick Bosa, Trent Williams and Brock Purdy.

Patrick goes over some of his biggest keys to a 10th Buffalo victory this season, including having the ability to shake off any rust early and don't let the turnover tendencies that've went there way flip around. From there it's bold predictions and among other things Patrick thinks it's time for rookie return man Brandon Codrinton to make a house call. That plus potential weather issues, a final score prediction and more.

Major props to Talking Buffalo sponsor, Sonny Red’s at 1841 Abbott Road in Lackawanna, just minutes from Highmark Stadium. We consider them THE most underrated spot for wings, pizza and other great food in Western New York plus it’s a great place to drink and have a great time.

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