The NFL's first Tuesday night game since Dec. 28, 2010 was not kind to the Buffalo Bills, who got trucked by the Titans — both literally and figuratively — in a 42-16 loss, their first of the season. Host Ryan O'Leary and Bills Wire editor Nick Wojton discuss went wrong and where the Bills go from here. (With fantasy football advice from The Huddle, and sports betting tips of the week from The Sportsbook Wire.)

When Josh Allen disappeared to the locker room with a left shoulder injury, Bills Mafia held its collective breath. He really is an MVP candidate this year. These 4-0 Bills would be lost without him. Host Ryan O'Leary and Bills Wire editor Nick Wojton discuss in Episode 6 of the Bills Wire Podcast.

More Josh Allen magic kept the Bills undefeated at 3-0 on the season, but it's hard to ignore the 28-3 lead the Rams quickly erased in the second half. Host Ryan O'Leary and Bills Wire editor Nick Wojton discuss another monster game from Allen, and a Bills defense that had no answers for the Rams in the second half. Should Bills fans be concerned?

QB Josh Allen is off to an amazing start passing the football, and his Bills are 2-0 atop the AFC East. But is it too soon to be mentioning Allen's name with Russell Wilson in NFL MVP talks? Host Ryan O'Leary and Bills Wire editor Nick Wojton discuss.

Host Ryan O'Leary and Bills Wire editor Nick Wojton analyze the Bills' 27-17 win over the lowly N.Y. Jets, including QB Josh Allen's first career 300-yard game. There was some good, some bad and some ugly in the Bills getting to 1-0 on the 2020 season.

Host Ryan O'Leary and Bills Wire editor Nick Wojton discuss Tre White's new lucrative contract extension, and why White and the Bills are poised to smother the Jets' receivers in their 2020 season opener.

Host Ryan O’Leary and Bills Wire managing editor Nick Wojton discuss the moment Buffalo Bills fans have been waiting for: The impending demise of the New England Patriots. Tom Brady’s in Tampa Bay. Stefon Diggs is in Buffalo. The Bills’ time is now. Will they seize their moment? 

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