BMJ talk medicine

Snoring is common. In the 30- to 35-year-old age group, 20% of men and 5% of women snore. By 60, 60% of men and 40% of women will snore habitually.

And snoring can affect the quality of life - of both the patient and their partner.

In this BMJ Best Practice podcast on snoring, Kieran Walsh talks with Dr Showkat Mirza, Consultant in Otorhinolaryngology and Head & Neck Surgery, Sheffield Teaching Hospitals NHS Trust.

For more on snoring, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/1035

Competing interests: SM has no competing interests

If you’ve ever wondered why tests sometimes don’t really work when you start using them then you’ll really want to listen to this episode .. or read this instead - https://adc.bmj.com/content/108/5/411.2

Or maybe you’ve lain awake at night worrying about how common portal vein thrombosis is in neonates and what that might mean for the baby … again, you’ll really want to get your ears attached to this podcast and take a few minutes to admire the search strategy here - https://adc.bmj.com/content/108/5/411.1

We would love for you to be involved in Archi [adc.bmj.com/pages/authors/#archimedes] - just ask the questions that your patients are offering you.

Please listen to our regular podcasts and subscribe in Apple Podcasts, Google Podcasts, Stitcher and Spotify to get episodes automatically downloaded to your phone and computer. And if you enjoy the podcast, please leave us a review at https://podcasts.apple.com/gb/podcast/adc-podcast/id333278832

In this episode of the Heart podcast, Digital Media Editor, Professor James Rudd, is joined by Professor Sarah Zaman from the University of Sydney, Australia. They discuss her systematic review and meta-analysis of the effect of this diet specifically in women, something not previously studied. If you enjoy the show, please leave us a podcast review at https://itunes.apple.com/gb/podcast/heart-podcast/id445358212?mt=2

Link to published paper: https://heart.bmj.com/content/early/2023/02/14/heartjnl-2022-321930

In this episode of the IJGC podcast, Editor-in-Chief, Dr. Pedro Ramirez, is joined by Dr. Giuseppe Caruso discuss post-PARP myeloid neoplasms. Dr. Caruso is a fifth-year resident in Obstetrics and Gynecology and a first-year fellow of the PhD in “Network Oncology and Precision Medicine” at Sapienza University of Rome in Italy. Over the past year, he has been attending the Department of Gynecologic Oncology at the European Institution of Oncology (Milan) under the mentorship of Professor Nicoletta Colombo and has now started his research fellowship period at Mayo Clinic (Rochester) under the supervision of Professor William Cliby. His main interest areas are gynecologic oncology, personalized oncology, and clinical research.

Highlights:

- Myeloid neoplasms post PARPi in patients with ovarian cancer are gradually emerging as life-threatening late toxicities and should not be underestimated.

- The first two years of PARPi exposure are the critical window of onset and persistent cytopenia has been recognized as an early warning sign.

- Active surveillance, differential diagnosis, and prompt hematological referral are crucial.

- PARPi are recommended in the first line also to improve the risk-benefit ratio.

- PARPi should be used cautiously in patients with a higher baseline risk and/or those who are less likely to have a significant benefit.

Helen Macdonald, Juan Franco, and Joe Ross are back with our monthly update on the world of evidence based medicine.

This episode delves into new methodologies which can use observational data to emulate trial data. We discuss a new systematic review and meta-analysis of RCTs for surgical treatment of sciatica. There is elaboration and explanation of the CONSORT Harms 2022 statement - and we'll be asking if it goes far enough. Finally, the old chestnut of surrogate endpoints in cancer treatment trials - are benefits communicated to patients accurately?

Reading list;

Nirmatrelvir and risk of hospital admission or death in adults with covid-19: emulation of a randomized target trial using electronic health records - https://www.bmj.com/content/381/bmj-2022-073312

Surgical versus non-surgical treatment for sciatica

https://www.bmj.com/content/381/bmj-2022-070730

CONSORT Harms 2022 statement, explanation, and elaboration

https://www.bmj.com/content/381/bmj-2022-073725

Funders crack down on unpublished clinical trials—but is it enough?

https://www.bmj.com/content/381/bmj.p840

Communication of anticancer drug benefits and related uncertainties to patients and clinicians

https://www.bmj.com/content/380/bmj-2022-073711

Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Benoit Chassaing, group leader from the “Mucosal microbiota in chronic inflammatory diseases” Team at INSERM and the Université Paris Cité, Paris, France, on the paper 'Akkermansia muciniphila counteracts the deleterious effects of dietary emulsifiers on microbiota and host metabolism' published in paper copy in Gut in May 2023 and available online: https://gut.bmj.com/content/72/5/906

Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).

In this co-interview, both Dr Philip Smith, Deputy Editor of FG and Social Media Associate Editor and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, and Dr Vivek Goodoory, Frontline Gastroenterology trainee editor, Clinical Research Fellow and Registrar in Gastroenterology at Leeds Teaching Hospitals NHS Trust, interview Dr Nasar Aslam, Endoscopy Research fellow at University College London Hospitals NHS Foundation Trust, on the paper 'Minimally invasive endoscopic therapies for gastro-oesophageal reflux disease’, published in Frontline Gastroenterology: https://fg.bmj.com/content/14/3/249.

Listen to our regular podcasts and subscribe in Apple Podcasts, Google Podcasts, Stitcher and Spotify. If you enjoy our podcast, please rate us on your chosen platform, and leave us a review on the Frontline Gastroenterology Podcast page on iTunes: https://podcasts.apple.com/gb/podcast/fg-podcast/id942944229

Rick Body, University of Manchester and Manchester University NHS Foundation Trust, and Sarah Edwards, University Hospitals of Derby NHS Foundation Trust, cover the pick of the papers from EMJ's May 2023 issue. In this edition, we cover papers on shoulder dislocation, blunt chest trauma, uterine bleeding, medical errors, benign paroxysmal position vertigo, and calcium and QTc interval.

Read the highlights: https://emj.bmj.com/content/40/5/317

You can subscribe to the EMJ podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month.

If you enjoy our podcast, please consider leaving us a review or a comment on the EMJ Podcast iTunes page (https://podcasts.apple.com/us/podcast/emj-podcast/id445358244).

Thank you for listening!

In this episode of the IJGC podcast, Editor-in-Chief, Dr. Pedro Ramirez, is joined by Dr. David Cibula to discuss the 2023 ESGO-ESTRO-ESP Guidelines for Cervical Cancer. Dr. Cibula is the Chair of the Department of Obstetrics and Gynecology at the General Faculty Hospital in Prague, Professor at the First Medical Faculty of the Charles University, Chair of the Central and Eastern European Gynaecologic Oncology Group (CEEGOG), member of the Strategic group of the ENGOT (European Network for Gynaecological Oncological Trial Groups) as well as a Former ESGO president.

Highlights:

- Multidisciplinary clinical practice guidelines developed jointly by ESGO/ESTRO/ESP in the field of gynaecological oncology, radiation oncology and pathology.

- Guidelines cover the management of all stages of cervical cancer, including separate sections dedicated to pathology reporting and management in pregnancy.

- The guidelines include recommendations, algorithms, and summaries of recent evidence published as supplements.

On this episode of the AMSSM (T: @TheAMSSM) Sports Medcast, host Dr. Jake Wessels, MD, is joined by Dr. Stacy Sims, MSc, PhD (Insta: @drstacysims), to discuss her upcoming lectures on how nutrition affects performance during the 2023 AMSSM Annual Meeting.

Dr. Sims is an international exercise physiologist and nutrition scientist. She has directed research programs at Stanford, AUT University, and the University of Waikato, focusing on female athlete health and performance and pushed to improve research on all women. Her contributions to the international research environment and the sports nutrition industry has established a new niche in sports nutrition; and established her reputation as the expert in sex differences in training, nutrition and health. Dr. Sims has published over 70 peer-reviewed papers and several books.

In this conversation, Dr. Sims addresses the following topics:

* How her athletic background impacted her journey into the field of nutrition and performance

* Sharing a starting point for medical professionals to think about optimizing nutrition for athletes

* Ways to encourage athletes to be aware of their nutrition and how to effectively structure training sessions and nutritional plans

* Her standard approach on supplementation and why less can often be more

Learn more about her work and publications on her website (drstacysims.com), and register to attend the 2023 AMSSM Annual Meeting in-person or virtually at annualmeeting.amssm.org.