BMJ talk medicine

Dr. Amy Ross Russell(1) is joined by a selection of the authors of "Toxic neuropathies; a practical approach", a review recently published in Practical Neurology. The guests, Dr. Duncan Smyth(2), Dr. Aisling Carr(3) and Prof. Michael Lunn(3), explain the background to these conditions and describe approaches to treatment and care of toxic neuropathy patients.

Read this latest Editor’s Choice paper on the Practical Neurology website (https://pn.bmj.com/content/23/2/120) and the April print issue of the journal.

The paper is also discussed by Practical Neurology editors, Dr. Phil Smith and Dr. Geraint Fuller, in their latest podcast: https://soundcloud.com/bmjpodcasts/editors-highlights-of-the-april-2023-issue?in=bmjpodcasts/sets/pn-podcast

(1) Neurology, University Hospital Southampton NHS Foundation Trust, UK

(2) Dept. of Neurology, Wellington Hospital, Wellington, NZ

(3) MRC Centre for Neuromuscular Diseases, National Hospital for Neurology, University College London Hospitals, UK

Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month.

If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053).

The PN podcast is produced by Letícia Amorim and edited by Brian O'Toole.

Thank you for listening.

In this episode of the IJGC podcast, Editor-in-Chief, Dr. Pedro Ramirez, is joined by Dr. Janos L. Tanyi to discuss intraoperative imaging with OTL38 in ovarian cancer. Dr. Tanyi is an associate professor in the Department of Obstetrics and Gynecology at The University of Pennsylvania. He developed an advanced immunotherapy program that allows patients’ own immune cells to recognize and kill their tumor; a gene-engineered T cell approach. Dr. Tanyi has a broad background in immunotherapy, cancer immunology, molecular genetics and clinical expertise in gynecologic oncology. He has the frontline experience in ovarian cancer immunotherapy as he is the primary PI for both the ovarian cancer vaccine and adoptive T cell transfer trials at University of Pennsylvania. At Penn, he has fostered the establishment of a rich translational research environment focused on ovarian cancer. Furthermore, Dr. Tanyi led the Phase 2 and 3 trials evaluating the efficacy and safety of Pafolacianine Sodium combined with intraoperative molecular imaging during cytoreductive surgery of ovarian cancer.

Highlights:

- It is well known that the extent of residual disease after surgery is negatively correlated with patient survival in ovarian cancer. To achieve R0 complete cytoreduction remains the goal of surgery. In this phase III study, it was evaluated whether Cytalux, would identify cancer lesions not identified by the surgeon by white light visual inspection or palpation.

- During this phase 3 trial, one or more additional cancer lesions were identified in approximately 33% of patients using of Cytalux with near-infrared imaging which was not detected by white light visual inspection and manual palpation.

- The intraoperative use of Cytalux with near-infrared imaging can be a good adjunct to current surgical approaches in identifying additional cancer lesions during cytoreductive surgery.

In this podcast, Brooke Patterson hosts Dr Erik Denison (PhD, Research Fellow Monash University) and Neil Hay (Rugby Victoria President) about a trial published in the BJSM which tested the effectiveness of an education program delivered by professional rugby players designed to stop homophobic language. They discuss openly and honestly the challenges in changing behaviour in community sport. It is not too often we get to chat to sports administrators more broadly about what is needed to drive change – whether it be related to health, safety, inclusion, or diversity. Should we be using the carrot or stick? What other strategies might work? What is your role as a clinician in creating a safe environment?

https://bjsm.bmj.com/content/early/2023/02/09/bjsports-2022-105916

https://bjsm.bmj.com/content/early/2023/02/07/bjsports-2022-105917

Given the current working conditions in the UK, we’re hearing more and more stories of doctors moving abroad to practise medicine. However, this isn’t necessarily unusual. Doctors and other healthcare professionals from many different countries do often decide to get a taste for healthcare systems elsewhere either through short, temporary placements, or through a more permanent move!

In today’s episode we’re going to be talking all about why students or junior doctors might be considering working abroad. We’ll also talk about the pros and cons of moving to a different country to work, and whether the grass really is greener on the other side. We’ll finish off by talking about the logistics of making such a move, and hear some top tips from our expert guest!

Expert guests:

Dr Matt Morgan is an intensive care consultant, researcher, and author. He currently works in Perth, Western Australia. He is also a columnist for The BMJ and works with BMJ OnExamination.

Check us out on social media:

Twitter: https://twitter.com/BMJStudent

Instagram: https://www.instagram.com/bmj_student/

Facebook: https://www.facebook.com/BMJStudent/

This podcast is produced and edited by Dom Byrne and Duncan Jarvies.

ADC Fetal and Neonatal’s Associate Editor, Jonathan Davis, and the Edition Editor of the journal, Ben Stenson, discuss the highlights from the March 2023 issue. The Fantoms article: https://fn.bmj.com/content/108/2/95

Additional links:

Caffeine Therapy for Apnea of Prematurity

https://www.nejm.org/doi/full/10.1056/nejmoa054065

Survival Without Disability to Age 5 Years After Neonatal Caffeine Therapy for Apnea of Prematurity

https://jamanetwork.com/journals/jama/fullarticle/1104870

Survival Without Disability to Age 5 Years After Neonatal Caffeine Therapy for Apnea of Prematurity

https://jamanetwork.com/journals/jama/fullarticle/1104865

Academic Performance, Motor Function, and Behavior 11 Years After Neonatal Caffeine Citrate Therapy for Apnea of Prematurity

https://jamanetwork.com/journals/jamapediatrics/fullarticle/2617993

Please listen to our regular podcasts and subscribe in Apple Podcasts, Google Podcasts, Stitcher and Spotify to get episodes automatically downloaded to your phone and computer. And if you enjoy the podcast, please leave us a review at https://podcasts.apple.com/gb/podcast/adc-podcast/id333278832

Gastro-oesophageal reflux disease (GORD) is a common condition that affects between 10% and 30% of people in developed countries.

There can be a range of complications from haemorrhage to stricture to Barrett's oesophagus. So it is important that we get the diagnosis and management of this condition right.

In this BMJ Best Practice podcast on GORD, Kieran Walsh talks with Dr Andres Carrion, Associate Professor of Clinical Medicine at The Division of Digestive Health and Liver Diseases in University of Miami Miller School of Medicine.

For more on GORD, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/82

Competing interests: None

In this episode of the Heart podcast, Digital Media Editor, Professor James Rudd, is joined by Dr Rachel M J van der Velden from Maastricht in The Netherlands. They discuss the use of mobile devices for detecting recurrences of AF in high-risk subjects and how acceptable this is to patients. If you enjoy the show, please leave us a podcast review at https://itunes.apple.com/gb/podcast/heart-podcast/id445358212?mt=2

Link to published paper:

https://heart.bmj.com/content/109/1/26

In this episode of the IJGC podcast, Editor-in-Chief, Dr. Pedro Ramirez, is joined by Laura Chambers to discuss the low-risk population in advanced ovarian cancer. Laura Chambers, DO is an Assistant Professor in the Division of Gynecologic Oncology at The James Cancer Center at The Ohio State University.

Highlights:

- Discuss historical perspectives of low and high-risk ovarian cancer, and how this has been analyzed in contemporary trials

- Review of contemporary trials for PARPi and Bevacizumab maintenance in women with advanced ovarian cancer

- Data obtained through un-powered sub-analysis from randomized clinical trials is hypothesis generating and care must be exercised in applying this to patient cohorts

In this episode of the IJGC Podcast, Editorial Fellows, Giulio Bonaldo and Jennifer Davies-Oliveira, discuss the contents of the March Special issue of IJGC.

In this episode of the IJGC Podcast, Editorial Fellows, Núria Agustí and Ryan Kahn, discuss the contents of the February issue of IJGC.