This compilation of excerpts centers on Joe Pitt, a vampire living in the Bronx, navigating a complex world of covert vampiric clans and the constant threat of discovery by "wilders", other dangerous infected individuals. Pitt is entangled in a perilous mission, initially assigned by Dexter Predo, a powerful Coalition figure, to gather intelligence on Amanda Horde, who seeks a cure for the Vyrus that causes vampirism. His journey takes him from the gritty streets of the Bronx, where he struggles with his identity and the isolation of his condition, to a hidden blood farm in Queens run by the Coalition, and ultimately to the Enclave, a fanatical group of vampires led by the Count and his second-in-command, Simon, who embrace the Vyrus as a path to power. Along the way, Pitt grapples with past relationships, including with Esperanza, a former associate of a dangerous figure named Lament, and the former Enclave leader's confidante, all while his own survival hangs in the balance amid shifting loyalties and impending inter-clan warfare.