As Walt calls Skyler's bluff and moves back home without her consent, Jesse ponders re-entering the drug trade, as a Mexican cartel anxiously awaits its opportunity to get revenge for the death of one of its own.

As he finds Skyler is dead set on getting a divorce, an unwitting Walt lands squarely in the crosshairs of a pair of Mexican drug cartel hit men set on revenge.

In the wake of the Albuquerque airline disaster, Skyler forces Walt to move out, while Jesse's stay in drug rehab helps him come to grips with his role in the fatal mid-air collision.

Walt's lies start to unravel, and Skyler's frustration with his secrecy finally comes to a head. Meanwhile, Jesse self-destructs when Jane overdoses and Donald's grief leads to tragedy.

The Whites welcome a new addition; Walter Jr. launches a new website; Jesse's addiction begins to get out of control; Jane and Jesse's relationship causes friction with both Walt and Donald.

Saul proposes a new business partner for Walt and Jesse, Skyler makes a shocking discovery at work, and Jesse opens up, telling recovering addict Jane what he does for a living.

Walt and Hank get into a heated argument at a party, Skyler opens up to her boss, and Jane tries to hide her relationship with Jesse from her father.

Walt undergoes scans after becoming convinced that his health is deteriorating. Meanwhile, Jesse's relationship with Jane is put on hold when he and Walt head into the desert for a marathon meth-cooking session.

When Badger gets into trouble with the law, Walt and Jesse seek advice from a shady attorney. Elsewhere, the DEA agents believe they have finally caught up with Heisenberg.

Jesse's new reputation as a killer means he and Walt are having no trouble collecting payment, so the duo discuss expanding into new territories. Meanwhile, Hank is struggling to fit in, and Skyler spies a new job opportunity.