Generalized pustular psoriasis is a rare inflammatory skin disease that can be life-threatening if left untreated, and treatment typically involves the use of therapies approved for plaque psoriasis. However, that could all be changing thanks to the recent understanding of IL-36’s role in generalized pustular psoriasis and the development of the treatment option spesolimab. Learn more with Dr. Raj Chovatiya and Dr. Jason Hawkes, medical dermatologist in the Greater Sacramento area who also sits on the National Psoriasis Foundation Medical Board and Scientific Advisory Committee.