Why Health Econoics Plays a Big Role in Clinical Trials

Health economics is used in clinical trials to ensure information is being collected in the right way so that it can be provided to the minister or committees such as the Pharmaceutical Benefits Advisory Committee so that they can compare new treatments with existing treatments to decide what drugs should be funded in the public system.

We asked Associate Professor De Abreu Lorenco to explain what health economics is, and how it is currently used in clinical trials.

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Guest: Professor Richard De Abreu Lorenco

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Comparing NASHA Gel vs. Surgical Clips: New Research in Breast Cancer

Radiation therapy after breast-conserving surgery plays an important role in the management of early breast cancer, decreasing the risk of breast cancer returning and improving mortality rates.

Dr Janice Yeh is evaluating the technical feasibility and clinical performance of the novel NASHA gel compared to standard surgical clips as a fiducial marker.

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Guest: Dr Janice Yeh

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What it's Like to Participate in a Cutting-Edge Clinical Trial

Madelaine Atkins was 50 when she was first diagnosed with breast cancer, in 2008, after finding a small lump in her right breast.

Despite receiving chemotherapy, radiation, and having surgery to remove her right breast, unfortunately, in 2011, Madelaine was diagnosed with Advanced Breast Cancer in her shoulder, neck, and lymph nodes.

After discussing further treatment options with her oncologist, Madelaine decided to participate in the FINER clinical trial. We spoke with Madelaine about her diagnoses, her decision to participate in the FINER clinical trial, and advice to other women who have received a diagnosis.

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Guest: Madelaine Atkins, FINER Clinical Trial Participant

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The BRCA-P Clinical Trial: A New Path for Breast Cancer Prevention

Katharine and Skye had never met each other, but they shared something in common. Both women carry the BRCA-1 gene mutation. This is an inherited gene that increases their chance of developing breast cancer by 70% and ovarian cancer by 40% throughout their lifetime.

Until now, life-changing invasive surgery and regular breast screening have been the only options available for women like Katharine and Skye. However, the BRCA-P clinical trial aims to open up a new treatment opportunity for women with this gene mutation.

BRCA-P is a preventative trial, which is testing the effectiveness of a drug called Denosumab in preventing breast cancer for these women.

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Guests: Skye and Katharine, BRCA-P Clinical Trial Participants

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Race for a Cure: How Families are Making a Difference

Ben and Michael Kavich are brothers and race car drivers, who are asking you to support life-saving breast cancer trials research by donating to Race for a Cure. Race for a Cure was founded by Ben's wife, Toula, after she was diagnosed with breast cancer following the Bathurst 6 Hour in 2016.

Toula's disease shocked the Kavich family who had already lived through the harrowing impact of breast cancer after Ben and Michael's grandmother and mother were diagnosed.

The brothers are using their passion for motorsport to help spare as many families as possible from the heartache and loss caused by breast cancer.

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Guests: Ben and Michael Kavich

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Diagnosed at 31: The Journey of a Young Breast Cancer Patient

At just 31 years old, Laura found a lump in her breast and was shortly after diagnosed with breast cancer.

We spoke with Laura about her shock diagnosis, her decision to participate in the Breast MRI Evaluation Study, and her advice to other young women who have also received a diagnosis.

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Guest: Laura McCambridge

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Hand and Foot Syndrome: A Side Effect You Should Know About

A side effect of some chemotherapy and targeted breast cancer treatments is Hand and Foot syndrome, also known as hand-foot syndrome, Palmar-Plantar Erythrodysesthesia, or PPE.

We spoke with Senior Podiatrist Rebecca Angus about the symptoms of the side effect and how it's treated.

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Guest: Rebecca Angus

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Living with a BRCA1 Gene Mutation: One Woman's Experience

Dimity Paul knew she carried an 80% risk of developing breast cancer since she was 21 years old, although it still came as a huge shock when she was diagnosed with breast cancer at 31.

She spoke with us about her experience with the BRCA1 gene mutation, her participation in the OlympiA clinical trial, and how being a part of a supportive workplace helped her through her treatment.

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Guest: Dimity Paul

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Taking Charge of Your Breast Cancer Risk: What You Can Do Today

Samantha was only 21 years old when she found out she had the BRCA1 gene mutation. This means she has a 70% risk of developing breast cancer and a 40% risk of developing ovarian cancer. She spoke with us about her decision to participate in the BRCA-P clinical trial.

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Guest: Samantha, BRCA-P Clinical Trial Participant

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Partial Breast Irradiation: Is it Right for You?

In this podcast episode, we spoke with Professor Julia White, a tenured Professor of Radiation Oncology and Koltz Sisters Chair for Cancer Research at the Ohio State University, about partial breast irradiation.

We discuss the different types of this treatment, who it is best suited for, and how research is being continued in this area.

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Guest: Professor Julia White

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