They're big, they're bold, but they've been bleeding red through investors' portfolios. Over the past 12 months, ASX darlings CSL (ASX:CSL), Brambles (ASX:BXB) and Coles (ASX:COL) have haemorrhaged 15.69%, 2.67% and 2.23%, respectively, making them the only three S&P/ASX20 stocks to fall into the red over the past year. 

So is it time to cut our losses or top-up? In this episode of Buy Hold Sell, we are sending these three big caps to the surgeon's theatre to see whether an economic infusion or two can bring these stocks back to life. 

Centennial Asset Management's Matthew Kidman is joined by Airlie Funds Management's Emma Fisher and Alphinity Investment Management's Stuart Welch to throw on some scrubs and put these three red giants under the knife. 

Plus, our fundies share one S&P/ASX20 stock that they believe still has plenty of upside ahead of it. 

Note: This episode was filmed on 30 March 2021.