🚨 New Study Alert 🧬🫀

Think a CAC score of zero means you're in the clear? Think again.

A massive cohort from the Western Denmark Heart Registry (n = 23,777) shows that elevated LDL-C is strongly associated with non-calcified plaque 🧱 and future coronary events 💥—even in those with CAC = 0.

📈 Each 1 mmol/L (~39 mg/dL) rise in LDL-C increases the odds of plaque (aOR 1.21) and risk of CHD (aHR 1.28).

🔥 Risks were highest in individuals ≤45 years—a silent threat during prime decades of life.

💡 Takeaway: No calcium ≠ No risk. LDL-C still drives subclinical disease.

👩‍⚕️👨‍⚕️ Time to rethink statin strategy in younger adults with "reassuring" scans.

📚 Read more in European Heart Journal (2025):

👉 https://doi.org/10.1093/eurheartj/ehaf497

#LDL #CAC #Cardiology #Atherosclerosis #CHD #Prevention #Lipidology #CCTA #PrecisionMedicine #Statins #EHJ #SubclinicalDisease #CardioLinked