In this episode of Health Matters, host Courtney Allison is joined by Dr. Rekha Kumar, endocrinologist and primary care physician at NewYork-Presbyterian and Weill Cornell Medicine, to unpack the science behind aging well. They discuss biohacking, longevity, and health span, separating evidence-based strategies from social media hype and exploring what truly helps us age well.

What You’ll Learn in This Episode

What “biohacking” really means

● How biohacking ranges from simple lifestyle optimization to high-tech, experimental interventions

● The difference between lifespan (how long you live) and health span (how long you live well)

The Longevity Pyramid

● Why the foundation of healthy aging is built on:

• Sleep
• Movement and strength training
• Nutrition
• Stress management
• Social connection

● How advanced tools and supplements sit at the top—and why they should never replace the basics

Wearables and Tracking

● How devices like smartwatches, glucose monitors, and fitness trackers can support behavior change

● When tracking becomes counterproductive or stressful

Peptides and “Anti-Aging” Supplements

● What’s proven (e.g., metformin, GLP-1 receptor agonists)

● What’s still experimental or under-studied (BPC-157, sermorelin, NAD boosters)

Nootropics and Cognitive Enhancers

● Everyday nootropics like caffeine

● The role of L-theanine for “calm focus”

● Myths around perfectly timed caffeine and cortisol rhythms

Nutrigenomics and Personalized Nutrition

● How genes can influence responses to foods (e.g., lactose intolerance, APOE and saturated fat)

● Why many direct-to-consumer genetic tests may overpromise

The Gut Microbiome

● The role of Akkermansia muciniphila in metabolic health

● How medications like metformin and GLP-1s may positively shift gut bacteria

● What’s still unknown about probiotic supplementation

Genetic and Biomarker Testing

● The difference between actionable medical insights and “information overload”

● Why results of unknown significance can cause unnecessary anxietyThe Big Takeaways

● There are no true shortcuts to longevity

● Sustainable habits beat quick fixes

● Our biology is built for rhythms, not constant optimization

Featured Expert

About Rekha B. Kumar, M.D., M.S.

Dr. Rekha B. Kumar is an attending endocrinologist at NewYork-Presbyterian/Weill Cornell Medical Center and an associate professor of Clinical Medicine at Weill Cornell Medicine. She specializes in adult primary care and endocrinology and has academic expertise in the diagnosis and treatment of various endocrine disorders, including obesity/weight management, type 2 diabetes, polycystic ovarian syndrome (PCOS), thyroid disorders, as well as metabolic bone disease.

Dr. Kumar completed her undergraduate studies at Duke University and received her masters degree in Physiology from Georgetown University. She received her M.D. from New York Medical College and completed her residency training in Internal Medicine at NewYork-Presbyterian/Weill Cornell Medical Center. Dr. Kumar obtained her clinical fellowship in the combined Diabetes, Endocrinology, and Metabolism program at the NewYork-Presbyterian/Weill Cornell Medical Center and the Memorial Sloan Kettering Cancer Center. Dr. Kumar is Board Certified in Internal Medicine, Endocrinology, Diabetes, & Metabolism, and Obesity Medicine.

Coming Up Next

In the next episode of Health Matters, we’ll explore brain health and the short- and long-term effects of alcohol on the brain with Dr. Hugh Cahill. Subscribe and follow Health Matters on Apple Podcasts, Spotify, or wherever you listen to stay up to date with expert-driven conversations on living well at every stage of life.

About Health Matters

Health Matters is your bi-weekly dose of health and wellness information, from the leading experts. Join host Courtney Allison to get news you can use in your own life. New episodes drop each Wednesday.If you are looking for practical health tips and trustworthy information from world-class doctors and medical experts you will enjoy listening to Health Matters. Health Matters was created to share stories of science, care, and wellness that are happening every day at NewYork-Presbyterian, one of the nation’s most comprehensive, integrated academic healthcare systems. In keeping with NewYork-Presbyterian’s long legacy of medical breakthroughs and innovation, Health Matters features the latest news, insights, and health tips from our trusted experts; inspiring first-hand accounts from patients and caregivers; and updates on the latest research and innovations in patient care, all in collaboration with our renowned medical schools, Columbia and Weill Cornell Medicine.

To learn more visit: https://healthmatters.nyp.org