With Martine Gilard, MD, PhD, FESC, ex-President of French Society of Cardiology and President-elect EAPCI, Hospital Cavale Blanche, Brest - France, and Riccardo Asteggiano, MD, FESC, LARC (Laboratorio Analisi Ricerca Clinica), Turin - Italy In this interview, Martine Gilard joins Riccardo Asteggiano to discuss the long-term follow-up of patients with acute coronary syndrome. The main aspects of secondary prevention and of clinical control are debated and a clear indication of the follow-up of these complex patients in General Cardiology are given.