Sign up to save your podcasts
Or
Share CARTA: Imagining the Future of Anthropogeny - An Evolutionary Perspective on Human Cognitive and Behavioral Variation with Daniel Geschwind
Share to email
Share to Facebook
Share to X
Share to email
Share to Facebook
Share to X
Or
CARTA: Imagining the Future of Anthropogeny - An Evolutionary Perspective on Human Cognitive and Behavioral Variation with Daniel Geschwind
Human cognition and behavior are highly heritable and so is liability to disorders that affect them. This includes neuropsychiatric disorders such as schizophrenia and autism spectrum disorder (ASD). We have started to integrate genetic risk data with the emerging maps of gene regulation to study human specific aspects of gene expression and gene regulation. These analyses indicate that human specific aspects of gene regulation, such as genes regulated by human specific enhancers, are indeed enriched in mutations or common genetic variants that increase risk for ASD and allied neurodevelopmental disorders. This provides evidence that genetic elements underlying human brain evolution are particularly susceptible to disruption in disease. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Education] [Show ID: 38299]
View all episodes
By UCTV
1
11 ratings
Human cognition and behavior are highly heritable and so is liability to disorders that affect them. This includes neuropsychiatric disorders such as schizophrenia and autism spectrum disorder (ASD). We have started to integrate genetic risk data with the emerging maps of gene regulation to study human specific aspects of gene expression and gene regulation. These analyses indicate that human specific aspects of gene regulation, such as genes regulated by human specific enhancers, are indeed enriched in mutations or common genetic variants that increase risk for ASD and allied neurodevelopmental disorders. This provides evidence that genetic elements underlying human brain evolution are particularly susceptible to disruption in disease. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Education] [Show ID: 38299]
More shows like UC San Diego (Video)
View all
Osher WISE: Well-being and Integrative Science for Everyone (Audio)
60 Listeners
University of California Video Podcasts (Video)
7 Listeners
Robert Reich
35 Listeners
UC Berkeley Graduate Council Lectures (Video)
1 Listeners
CARTA - Anthropogeny (Audio)
7 Listeners
Oceanography (Audio)
39 Listeners
Mental Health and Psychiatry (Video)
17 Listeners
Aging and Senior Health (Audio)
19 Listeners
Public Policy and Society (Video)
1 Listeners
Stem Cell Channel (Video)
3 Listeners