Gordon Saxe, M.D., Ph.D., reveals the secrets to slowing down the aging process and living a healthier life. He uncovers how aging affects everything from our bones and muscles to our brain, leading to issues like memory loss, fatigue, and weakened immune responses.

How can you make choices today that could help you live longer and feel better? Saxe dives into groundbreaking research on caloric restriction, a powerful tool for extending lifespan, and how a plant-based diet can prevent chronic diseases and improve overall health. He also shares practical tips on exercise, stress management, and social connection that can help you stay sharp, strong, and energized as you age. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40322]

Pinar Yoldas, Ph.D., an artist and professor at UC San Diego, uses her background in neuroscience and architecture to create thought-provoking art that blends biology, technology, and design. Her work imagines new possibilities for a more compassionate and sustainable future, from algae-based plastics to sculptures inspired by the human brain. By exploring how human desires drive technological innovation, Yoldas challenges us to consider how creativity can shape our world. Series: "Arts Channel " [Arts and Music] [Show ID: 39862]

The current conflict between Israel and Gaza stems from long-standing tensions but was exacerbated after a major attack by armed groups from Gaza on October 7, 2023, resulting in over 1,200 Israeli deaths and 250 hostages being taken. This prompted a large-scale military response by Israel, including airstrikes and ground operations in Gaza, which have killed over 41,000 Palestinians, with tens of thousands more injured and displaced. The escalation in violence has also created a humanitarian crisis. The biggest question... will these hostilities ever come to an end? Is there hope for a two-state plan between Israel and Gaza? Using data driven analytics, Israeli policy expert Dahlia Scheindlin and Palestinian public opinion and polling expert Khalil Shikaki reveal the thoughts and mindsets of these two fighting populations and if peace is possible in the Middle East. Series: "Global Policy and Strategy" [Public Affairs] [Show ID: 40269]

Martin Kampmann, Ph.D., explores how CRISPR screening and induced pluripotent stem cell (iPSC) technology can uncover new insights into neurological diseases such as Alzheimer's. His lab uses CRISPR to identify genes that influence protein aggregation and cellular vulnerability, focusing on neurons, astrocytes, and microglia derived from human stem cells. Kampmann highlights the roles of mitochondria, autophagy, and other cellular pathways in disease progression, emphasizing the importance of understanding both protective and damaging processes. He also discusses the potential contributions of glial cells—especially microglia and astrocytes—to neurodegeneration, sparking ideas for therapeutic targets. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39461]

In this insightful conversation, Edward Abeyta, Ph.D., Associate Dean for Education and Community Outreach at UC San Diego Division of Extended Studies, shares his passion for lifelong learning, community access, and innovation in education. Drawing on his personal journey, shaped by his family’s belief in hard work and continuous learning, Abeyta underscores the importance making education accessible to all. He discusses his book, Reinventing Lifelong Learning: The Coming Renaissance of Continuing Education and Community Outreach, as a valuable resource for educators and policymakers looking to foster positive change. Abeyta highlights UC San Diego’s unique role in supporting learners at every stage of life—from youth to retirement—reinforcing his vision of education as a transformative force for individuals and communities alike. Series: "Education Channel" [Education] [Show ID: 40255]

Anthony Lim, M.D., J.D., explores how small, intentional steps can lead to lasting behavioral change. Lim breaks down a simple, four-step framework—awareness, intention, action, and reflection—to help people achieve their goals, whether it's improving health, forming better habits, or making positive life changes. Through real-life examples and insights from neuroscience, he emphasizes the power of connecting with your deeper "why," taking action, and practicing self-compassion. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40323]

Christine Wu Nordahl, Ph.F., offers an insightful exploration into the unique needs and experiences of autistic teens, focusing on fostering inclusive spaces. Highlighting themes of gender diversity, underdiagnosis in girls, and the impact of societal perceptions, she emphasizes the importance of tailored support for neurodiverse individuals. Through powerful participant stories and an inspiring poem, Nordahl underscores the resilience and creativity within the autistic community. Her passionate advocacy for better diagnostic tools and inclusive interventions makes this talk a must-watch for anyone seeking to understand and empower autistic youth. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Show ID: 40213]

Frank Furnari, Ph.D., and Alexander Khalessi, M.D., M.B.A., discuss exciting advancements in brain cancer research, focusing on glioblastoma, an aggressive and challenging tumor. They highlight how specific genetic mutations drive tumor growth and how targeting these mutations could lead to new treatments. They also delve into cutting-edge therapies, including using light to activate drugs aimed at combating cancer. A central theme of the talk is the complexity and ever-changing nature of these tumors, which makes them difficult to treat. However, technological breakthroughs, like single-cell genetic sequencing and lab-grown tumor models, are providing scientists with valuable insights into tumor behavior, paving the way for more personalized and effective treatment options in the future. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39871]

Everyone experiences mental chaos - when the mind is distracted, racing and anxious. But too much mental chaos can have negative impacts on our health and can limit our creativity. Jaime Pineda, professor emeritus of cognitive science at UC San Diego, has spent decades studying how the mind works. His new book “Controlling Mental Chaos: Harnessing the Power of the Creative Mind” focuses on the importance of psychological wellbeing. He says controlling mental chaos leads to positive outcomes including increased creativity, awareness of connection to others and reduction in distorted perceptions. He talks about ways to quiet the mind through mediation and mindfulness training. Series: "Library Channel" [Science] [Show ID: 40066]

Le Xu, Ph.D., examines the intricate processes underlying lung development and disease, with a focus on idiopathic pulmonary fibrosis (IPF). Xu explores the roles of genetic and cellular mechanisms, including the hedgehog pathway, FGF signaling, and epithelial-mesenchymal interactions, in driving lung fibrosis. Xu also highlights links between congenital diaphragmatic hernia (CDH) and lung development, suggesting that both mechanical and genetic factors contribute to lung hypoplasia. The discussion includes the development of advanced mouse models that replicate key aspects of human IPF, offering insights into fibrosis progression. Xu's research ultimately seeks to identify the causes of lung tissue abnormalities and pave the way for targeted therapies. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39460]