The question of acetaminophen versus ibuprofen may finally be laid to rest. A recent meta-analysis compared the efficacy and safety of ibuprofen versus acetaminophen for the treatment of fever or pain in children younger than 2 years. Is there a drug of choice?Reference: Tan E, Braithwaite I, McKinlay CJD, Dalziel SR. Comparison of Acetaminophen (Paracetamol) With Ibuprofen for Treatment of Fever or Pain in Children Younger Than 2 Years: A Systematic Review and Meta-analysis. JAMA Netw Open. 2020;3(10):e2022398. doi:10.1001/jamanetworkopen.2020.22398This episode is accredited for CPE. Subscribe at CEimpact (https://www.ceimpact.com/pharmacist) and claim your CE today!The CE for this episode is supported by an educational grant from Xellia Pharmaceuticals, a specialty pharmaceutical company focused on providing important anti-infective treatments against serious and often life-threatening infections. See omnystudio.com/listener for privacy information.

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In the never ending battle with COVID-19, new studies have demonstrated a role for IVIG in the treatment of acute COVID-19 pneumonia, the potential benefit of honey and black seed in mild to moderate COVID-19, and the efficacy of an mRNA vaccine. What does this all mean for current practice?Additional References:IVIG: Gharebaghi, N., Nejadrahim, R., Mousavi, S.J. et al. The use of intravenous immunoglobulin gamma for the treatment of severe coronavirus disease 2019: a randomized placebo-controlled double-blind clinical trial. BMC Infect Dis 20, 786 (2020). https://doi.org/10.1186/s12879-020-05507-4 Honey: Ashraf S, Ashraf S, Imran M, et al. Efficacy of honey and Nigella sativa against COVID-19: HNS-COVID-PK Trial. medRxiv 2020.10.30.20217364; doi: https://doi.org/10.1101/2020.10.30.20217364 Cleveland Clinic Hospitalization Risk for COVID-19 Positive Calculator: https://riskcalc.org/COVID19Hospitalization/ Cleveland Clinic Predict COVID-19 test result Calculator: https://riskcalc.org/COVID19/ This episode is accredited for CPE. Subscribe at CEimpact https://www.ceimpact.com/pharmacist and claim your CE today!The CE for this episode is supported by an educational grant from Xellia Pharmaceuticals, a specialty pharmaceutical company focused on providing important anti-infective treatments against serious and often life-threatening infections. See omnystudio.com/listener for privacy information.

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Atopic Dermatitis is not extensively taught in pharmacy curriculum. With several international medical societies publishing updated guidelines and newly approved medications, it's time for a review. Clinicians can learn ways to help treat patients under the skin.This episode is accredited for CPE. Subscribe at CEimpact (https://www.ceimpact.com/pharmacist) and claim your CE today!The CE for this episode is supported by an educational grant from Xellia Pharmaceuticals, a specialty pharmaceutical company focused on providing important anti-infective treatments against serious and often life-threatening infections. See omnystudio.com/listener for privacy information.

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The opioid epidemic is helping reduce prescriptions for opioid-based pharmacotherapy. However, parallel to this drop has been an increase in gabapentin and pregabalin prescriptions.  Why has this occurred and what should the clinician know about this phenomenon?Additional Resources/References: Trends, Patient and Prescriber Characteristics in Gabapentinoid Use in a Sample of United States Ambulatory Care Visits from 2003 to 2016. Zhou L, Bhattacharjee S, Kwoh CK, Tighe PJ, Malone DC, Slack M, Wilson DL, Brown JD, Lo-Ciganic WH. J Clin Med. 2019 Dec 29;9(1):83. doi:10.3390/jcm9010083.This episode is accredited for CPE. Subscribe at CEimpact (https://www.ceimpact.com/pharmacist) and claim your CE today!See omnystudio.com/listener for privacy information.

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Sodium Glucose Co-Transporter-2 Inhibitors, a medication class for the treatment of diabetes, is now showing benefits in other medical conditions, like heart failure and kidney disease. Is this a class effect?Additional Resources/References: McGuire DK, Shih WJ, Cosentino F, et al. Association of SGLT2 Inhibitors With Cardiovascular and Kidney Outcomes in Patients With Type 2 Diabetes: A Meta-analysis . JAMA Cardiol. Published online October 07, 2020. doi:10.1001/jamacardio.2020.4511This episode is accredited for CPE. Subscribe at CEimpact (https://www.ceimpact.com/pharmacist) and claim your CE today! See omnystudio.com/listener for privacy information.

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Vancomycin, despite being around for decades, keeps having updates to dosing, formulations, and monitoring. It's important to stay updated on this vital medication for hospital and infusion center practitioners. Are you ready for the changes?Additional Resources/References: https://www.idsociety.org/practice-guideline/vancomycin/This episode is accredited for CPE. Subscribe at CEimpact (https://www.ceimpact.com/pharmacist) and claim your CE today!The CE for this episode is supported by an educational grant from Xellia Pharmaceuticals, a specialty pharmaceutical company focused on providing important anti-infective treatments against serious and often life-threatening infections.  See omnystudio.com/listener for privacy information.

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A recently published Serial cross-sectional analysis of National Health and Nutrition Examination Survey data has been published suggesting that overall blood pressure control in adults with hypertension over the last 4 years has declined.Why is this? What tips can the pharmacist and prescriber use to improve control? Can these professionals work together to improve BP control? Can we survive under pressure?Additional Resources/References: Muntner P, Hardy ST, Fine LJ, et al. Trends in Blood Pressure Control Among US Adults With Hypertension, 1999-2000 to 2017-2018. JAMA. 2020;324(12):1190–1200. doi:10.1001/jama.2020.14545This episode is accredited for CPE. Subscribe at CEimpact (https://www.ceimpact.com/pharmacist) and claim your CE today!See omnystudio.com/listener for privacy information.

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The LoDoCo2 Trial suggested that colchicine may improve outcomes in patients with cardiovascular disease. Can a 3,000 year old drug still be a miracle?Additional Resources/References: Nidorf SM, Fiolet ATL, Mosterd A, et al; LoDoCo2 Trial Investigators. Colchicine in Patients with Chronic Coronary Disease. N Engl J Med. 2020 Aug 31. doi: 10.1056/NEJMoa2021372. Epub ahead of print. PMID: 32865380.This episode is accredited for CPE. Subscribe at CEimpact (https://www.ceimpact.com/pharmacist) and claim your CE today!See omnystudio.com/listener for privacy information.

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The fear of a "Twindemic," an influenza and COVID-19, double pandemic is starting to rise. But what does the data say about this fear? Is the US in double trouble with BOGO viral infections?This episode is accredited for CPE. Subscribe at CEimpact (https://www.ceimpact.com/pharmacist) and claim your CE today!See omnystudio.com/listener for privacy information.

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Updated osteoporosis guidelines have arrived from the American Association of Clinical Endocrinology. The AACE guidelines include different recommendations from the 2017 National Osteoporosis Foundation guidelines, primarily due to new anabolic agents. Learn about a newly created a new patient risk stratified category, the role of bisphosphonates, and how to approach patient care.Additional Resources/References:FRAX calculator: US version https://www.sheffield.ac.uk/FRAX/tool.aspx?country=9; AACE osteoporosis guidelineshttps://www.aace.com/disease-stateresources/reproductive-and-gonad/clinical-practiceguidelines-recent-news-and-updatesThis episode is accredited for CPE. Subscribe at CEimpact(https://www.ceimpact.com/pharmacist) and claim your CE today!See omnystudio.com/listener for privacy information.

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