Atopic dermatitis (AD) is the most common inflammatory skin disease. It has a complex pathophysiology, with a combination of immune dysregulation and intrinsic barrier defects driving cutaneous inflammation and allergic symptomatology.
See the original Article here:
https://www.researchgate.net/publication/352278907_The_IL-4_IL-13_and_IL-31_pathways_in_atopic_dermatitis
By Celina Dubin, Ester Del Duca & Emma Guttman-Yassky.