This episode is hosted by Pooja Dharwadkar, M.D, assistant professor at the University of California San Francisco, and features a discussion between Carol Burke, M.D, codirector of the Hereditary Cancer Clinic at the Cleveland Clinic; Robert Hüneburg, M.D, gastroenterologist at the National Center for Hereditary Tumor Syndromes at University Hospital Bonn in Bonn, Germany; and Bryson Katona, M.D, director of the GI Cancer Genetics and Cancer Risk Evaluation programs at the Hospital of the University of Pennsylvania in Philadelphia, PA. They discuss the benefits of upper GI cancer surveillance in Lynch syndrome – specifically as it applies to gastric cancer – and the studies that have contributed to recent updates in the National Comprehensive Cancer Network screening and surveillance guidelines for individuals with Lynch syndrome.  

This episode references the following articles:  

“Upper endoscopic surveillance in Lynch syndrome detects gastric and duodenal adenocarcinomas,” found here: https://pubmed.ncbi.nlm.nih.gov/32859614/
“Value of upper gastrointestinal endoscopy for gastric cancer surveillance in patients with Lynch syndrome,” found here: https://pubmed.ncbi.nlm.nih.gov/32930401/ 

“Clinically actionable findings on surveillance EGD in asymptomatic patients with Lynch syndrome,” found here: https://pubmed.ncbi.nlm.nih.gov/34252420/ 

This episode was recorded on July 9th, 2022 and reflects expert opinion at the time of the recording.  

On the occasion of the 2022 #PrevivorDay and #HereditaryCancerWeek, we're delighted to bring you a podcast debate as part of the CGA-IGC 2022 Podcast Series - Episode 6.

This episode is hosted by Michael J. Hall, MD, MS, Fox Chase Cancer Centre and features Heather Hampel, MS, CGC, City of Hope and Matthew B. Yurgelun, MD, Dana-Farber Cancer Institute.

The debate features Professor Heather Hampel and Dr Matthew Yurgelun going head to head over "Is it Time for Universal Germline Genetic Testing for All GI Cancers?", which was published in the Journal of Clinical Oncology can be found here https://pubmed.ncbi.nlm.nih.gov/35649230/

This episode was recorded on September 19th, 2022 and reflects expert opinion at the time of the recording.

This episode is hosted by Beth Dudley, MS, MPH, CGC, University of Pittsburgh Medical Center and features Michael G. Goggins, M.B.B.CH., M.D., The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions.

Together they discuss “The Multicenter Cancer of Pancreas Screening Study: Impact on Stage and Survival” which was published in the Journal of Clinical Oncology and found here: https://pubmed.ncbi.nlm.nih.gov/35704792/

This episode was recorded on June 21st, 2022 and reflects expert opinion at the time of the recording.

This episode is hosted by Joshua Sommovilla, M.D, The Sanford R. Weiss, MD Center for Hereditary Colorectal Neoplasia at the Cleveland Clinic and features Matthew Kalady, M.D, The Ohio State University Wexner Medical Center and Mohammad Abbas, M.D., MPH, Northwestern University.

Together they discuss “Evaluation of Urinalysis-Based Screening for Urothelial Carcinoma in Patients With Lynch Syndrome” which was published in the Journal of Dis Colon Rectum. and found here: https://pubmed.ncbi.nlm.nih.gov/34882627/

This episode was recorded on April 25th, 2022 and reflects expert opinion at the time of the recording.

This episode is hosted by Thomas (T.J.) Slavin, M.D.,FACMGG, PhD and features Rachel Hodan, MS, CGC, Genetic Counselor & Clinical Assistant Professor at Stanford University, Cancer Genetics Clinic and Kimberly Perez, MD, Gastrointestinal Medical Oncologist & Assistant Professor of Medicine, Dana Farber Cancer Institute.

Together they discuss “Patterns of germline and somatic testing after universal tumor screening for Lynch syndrome: A clinical practice survey of active members of the CGA-IGC” which was published in the Journal of Genetic Counseling and found here:  https://pubmed.ncbi.nlm.nih.gov/35218578/

The CGA Clinical Practice Survey 2022: Universal Germline Testing for Colorectal Cancer is currently open and CGA-IGC members are invited to participate.  Check your inbox for the survey link.

This episode was recorded on June 1st, 2022 and reflects expert opinion at the time of the recording.

This episode is hosted by Thomas (T.J.) Slavin, M.D.,FACMGG, PhD and features Bryson Katona, M.D., PhD, Director, Gastrointestinal Cancer Genetics Program & Assistant Professor of Medicine at the Hospital of the University of Pennsylvania; and Jessica Long, MS, CGC, Division of Hematology–Oncology, Department of Medicine at the University of Pennsylvania.  Together they discuss the article “EUS-based Pancreatic Cancer Surveillance in BRCA1/BRCA2/PALB2/ATM Carriers Without a Family History of Pancreatic Cancer” which was published in Cancer Prevention Research and found here: https://pubmed.ncbi.nlm.nih.gov/34341011/

Studies mentioned during the podcast

https://clinicaltrials.gov/ct2/show/NCT02478892?term=NCT02478892&draw=2&rank=1

https://clinicaltrials.gov/ct2/show/NCT02000089?term=CAPS5&draw=2&rank=1

https://clinicaltrials.gov/ct2/show/NCT04970056?term=PRECEDE&draw=2&rank=4

This episode was recorded on April 25th, 2022 and reflects expert opinion at the time of the recording.

This episode is hosted by Maureen May, MS, CGC and features Bronwyn Bedrick, M.D., M.S.C.I., who is a Gynecology and Obstetrics Resident Physician at Johns Hopkins Hospital.  Together they discuss the article “Creating Breast and Gynecologic Cancer Guidelines for Transgender Patients With BRCA Mutations,” which was published in Obstetrics & Gynecology and found here: https://pubmed.ncbi.nlm.nih.gov/34735408/

Resources mentioned during the podcast

This episode was recorded on March 3, 2022 and reflects expert opinion at the time of the recording.

This episode is hosted by Dr. Thomas Slavin (T.J.) and features Amy K. Otto, PhD, who is a Research Assistant Professor in the Department of Public Health Sciences at the University of Miami Miller School of Medicine.  Together they discuss the article “Impact of Patients' Companions on Clinical Encounters Between Black Patients and Their Non-Black Oncologists,” which was published in JCO Oncology Practice and found here: https://pubmed.ncbi.nlm.nih.gov/33411574/ 

This episode was recorded on August 26, 2021 and reflects expert opinion at the time of the recording.

This episode is hosted by Dr. Thomas Slavin (T.J.) and features Rachel Pearlman, MS, CGC, who is a Licensed, Certified Genetic Counselor and Assistant Professor in the Department of Internal Medicine at The Ohio State University Comprehensive Cancer Center. Together they discuss the article “Prospective Statewide Study of Universal Screening for Hereditary Colorectal Cancer: The Ohio Colorectal Cancer Prevention Initiative,” which was published in JCO Precision Oncology and found here: https://pubmed.ncbi.nlm.nih.gov/34250417/

This episode was recorded on August 10, 2021 and reflects expert opinion at the time of the recording.

This episode is hosted by Dr. Thomas Slavin (T.J.) and features Dr. Eduardo Vilar-Sanchez. Dr. Vilar-Sanchez is a medical oncologist at MD Anderson Cancer Center. Together they discuss “Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa,” which was published in Gut and found here: https://pubmed.ncbi.nlm.nih.gov/32641470/

This episode was recorded on March 26, 2021 and reflects expert opinion at the time of the recording.