Manager Thomas Frank left out six big names for the club's latest European campaign. Spurs' 25-man squad for their return to Europe's elite club competition doesn't feature Kota Takai, Radu Dragusin, Yves Bissouma, James Maddison, Dejan Kulusevski or Mathys Tel.

The omission of England international Maddison, 28, comes as no surprise. The midfielder suffered a potentially season-ending knee injury in the club's pre-season friendly against Newcastle in August.

Summer signing Takai is also in the treatment room with a plantar fascia injury, and his return date is currently unknown. Dragusin and Kulusevski haven't made the cut as they, like Maddison, are dealing with knee injuries. t's understood that Dragusin could be back to full fitness late next month. Sweden international Kulusevski, meanwhile, is on course to return in late November.

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