Liverpudlian comedian Chris McCausland gradually started losing his eyesight due to a hereditary condition called retinitis pigmentosa. His sight got so bad in his 20s that he was forced to give up his job as a web developer and ended up unemployed. He decided to give stand-up a try and is now a regular fixture on the comedy circuit. Tickets for his latest show, Yonks! are available at chrismccausland.com

Chris McCausland

Award-winning LBC presenter and best-selling author James O’Brien hosts a series of compelling conversations with fascinating people. These are revealing interviews with people who rarely give in-depth interviews, be it from politics, entertainment or news. Subscribe to get a new episode every Friday.

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Angela Hartnett is a Michelin starred chef, restaurateur and podcast host. After studying for a history degree, she began working in a local pub before joining Gordon Ramsay at his first restaurant, Aubergine. She worked with Gordon for 17 years before deciding to go it alone. She now runs several restaurants of her own including the Michelin-starred Murano in Mayfair. Angela's podcast, Dish from Waitrose, is available on all podcast providers.

Angela Hartnett: One of the UK's top chefs shares her recipe for success

In 2010 Caroline Lucas made history when she was elected as the MP for Brighton Pavilion, becoming the first Green Party candidate to enter Parliament. She has increased her majority at every election since and served as the Green leader twice. In her 14 years in Westminster, Caroline has used her platform to put environmental and equality issues on the political agenda. Her latest book, Another England sets out how we can reclaim England's national story from Brexit cheerleaders and the radical right.

Caroline Lucas: Being Britain's first and only Green MP

In 2011 Bassem Youssef was a little-known heart surgeon in Cairo. A year later, he was hosting his own political satire TV show, Al-Bernameg, drawing in 30 million weekly viewers as he made fun of the Egyptian regime. Bassem's comedy was groundbreaking but it proved too controversial to remain on air. In 2014 he was forced to move to United States, where he has since had to work to re-establish his career in a new language. Now, he's back in the news thanks to an explosive interview with Piers Morgan on the conflict in Gaza, which went viral.  Tickets for his latest tour, The Middle Beast, are available at livenation.co.uk

Bassem Youssef: Egypt's Jon Stewart on Palestine, the press and Piers Morgan

"The best ideas don't come from the boardroom, the best ideas come from the frontline."  James Timpson is the chief executive of Timpson, a family-run business known for its key cutting and watch repair services. James does business differently. His unconventional leadership style has raised eyebrows - but it works. Since taking over Timpson, he has grown the business to over 2,000 stores by developing new ideas, giving ex-prisoners a second chance and putting his employees first.  He has published a book packed with leadership advice for a happier, healthy workforce. The Happy Index: Lessons in Upside-Down Management is out now. 

James Timpson: The secrets to running a successful business and making money

Bryony Gordon is a bestselling author, mental health campaigner and founder of Mental Health Mates. She has been a columnist for the Telegraph for over twenty years where she has written honestly and openly about her experiences of mental illness and addictions. Her latest book, Mad Woman details her experiences of OCD, binge eating and the endless battle to stay sober. Bryony tells James about the realities of living with dark, intrusive thoughts and how exercise became her salvation. 

Chris McCausland

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