Chronic diarrhea affects approximately 6–7% of adults, and the vast majority of cases are noninfectious.

The most common causes are irritable bowel syndrome with diarrhea and functional diarrhea.

A systematic approach matters:

• Screen with CBC, CMP, fecal calprotectin, IgA-tTG

• Identify alarm features

• Biopsy for microscopic colitis when needed

• Start with lifestyle + low-FODMAP

• Escalate to targeted therapy thoughtfully

Precision in diagnosis leads to precision in therapy.

#Gastroenterology #InternalMedicine #EvidenceBasedMedicine