HIV has reshaped modern medicine — scientifically, socially, and ethically. This chapter explores HIV as a chronic condition, a public health challenge, and a lived experience shaped by stigma as much as virology.

In this audio deep dive, we examine viral replication, immune compromise, and the principles underpinning antiretroviral therapy. You’ll hear how early diagnosis, sustained treatment, and prevention strategies have transformed outcomes — while disparities in access continue to shape global impact.

This chapter situates HIV within a longer arc of care, resilience, and responsibility, emphasising continuity, dignity, and the importance of long-term therapeutic relationships.

Infectious disease sits at the crossroads of biology, behaviour, and environment. This chapter explores how pathogens interact with hosts, how infections present across organ systems, and why context matters as much as microbiology.

In this deep dive, we examine patterns of infection rather than isolated organisms — considering routes of transmission, host susceptibility, and the balance between immune response and tissue damage. You’ll hear how clinical reasoning integrates epidemiology, exposure history, and evolving presentations.

This chapter frames infectious disease as a dynamic process, shaped by global movement, inequality, and antimicrobial pressure. It invites clinicians to think systemically, recognising infection not as an isolated event, but as part of a wider ecological and social landscape.

Medicine in austere environments strips practice back to its essentials. This chapter explores how care is delivered when resources are limited, infrastructure is fragile, and improvisation becomes necessary.

In this audio deep dive, we consider clinical decision-making in remote, disaster, humanitarian, and low-resource settings. You’ll hear how prioritisation shifts, how diagnostic uncertainty increases, and how ethical decisions become inseparable from logistical realities.

This chapter reminds us that medicine is not defined by technology, but by adaptability, judgement, and human presence — even when conditions are harsh and support is distant.

Envenomation occupies a unique intersection between medicine, environment, and evolution. This chapter explores the effects of venom on the human body and the principles guiding assessment and treatment after bites and stings.

In this deep dive, we examine how venom acts systemically, how severity is assessed, and why geography and species knowledge matter. You’ll hear how antivenoms are used judiciously, why observation often precedes intervention, and how fear can distort early clinical judgement.

This chapter highlights the importance of calm, evidence-based response in situations that are often emotionally charged — for patients and clinicians alike.

Poisoning presents medicine with compressed timelines and hidden narratives. Substances enter the body silently, often before intention or consequence is fully understood. This chapter explores how clinicians identify, assess, and manage toxic exposures when certainty is scarce.

In this audio deep dive, we look at toxidromes, dose–response relationships, and the principles that guide decontamination, antidote use, and supportive care. You’ll hear why history-taking is often incomplete, why observation can be as important as intervention, and how risk evolves over time rather than at presentation.

This chapter reframes poisoning not as chaos, but as pattern — where careful reasoning, restraint, and anticipation matter more than dramatic action.

Acute medicine is where clinical knowledge meets time pressure, incomplete information, and physiological instability. This chapter explores how clinicians recognise deterioration, prioritise action, and make decisions when delay itself becomes a risk.

In this deep dive, we examine the early identification of critical illness, the principles of resuscitation, and the logic behind structured approaches to acutely unwell patients. You’ll hear how pattern recognition, physiology, and teamwork converge in moments where clarity must be forged from urgency.

Rather than focusing on individual conditions, this chapter attends to states — shock, sepsis, respiratory failure, altered consciousness — and the disciplined thinking required to stabilise first and diagnose second. It is a chapter about readiness, vigilance, and the calm application of fundamentals under pressure.

Pain and palliative care attend to what matters when cure is no longer the goal — or was never possible. This chapter explores suffering in its physical, emotional, and existential forms.

In this audio deep dive, we consider how pain is assessed, how symptoms are managed, and how care shifts when priorities change. You’ll hear how comfort, dignity, and meaning guide decision-making, and why listening is often the most potent intervention available.

This chapter reframes medicine as accompaniment — walking with, rather than fixing.

Oncology is a discipline shaped by complexity, uncertainty, and time. This chapter explores cancer as a biological process, a clinical journey, and a human experience.

In this deep dive, you’ll hear how malignancy develops, how it is staged and treated, and why multidisciplinary care matters. Beyond mechanisms and therapies, the chapter attends to toxicity, survivorship, and the ethical weight of decision-making when cure is uncertain.

This is a chapter about precision and compassion — and about holding hope without illusion.

Infectious diseases reveal medicine at its most dynamic — shaped by evolution, environment, and human behaviour. This chapter lays out the principles that underpin how infections arise, spread, and are controlled.

In this audio deep dive, we explore hosts, pathogens, and transmission without reducing infection to fear or combat. You’ll hear how prevention, diagnosis, and treatment are interwoven — and why antimicrobial resistance is not just a microbiological problem, but a cultural one.

This chapter reframes infection as a systems problem, where biology and society constantly interact.

Population health shifts the lens from the individual to the many — revealing patterns that no single consultation can show. This chapter explores how disease is measured, prevented, and understood at scale.

In this deep dive, you’ll hear how incidence, prevalence, screening, and risk intersect with policy, equity, and ethics. It examines why well-intentioned interventions can mislead, how bias distorts data, and why prevention often requires patience rather than immediacy.

This chapter invites clinicians to hold two perspectives at once: the person in front of them, and the population beyond the room.