Clinical Trials - The Bloodline with Blood Cancer United Podcast

Join us as we speak to Dr. Richard Larson and Dr. Anand Patel from University of Chicago Medicine about chronic myeloid leukemia (CML). In this episode, they discuss the latest advances in treatment for CML and what is on the horizon.

With decades of progress with targeted treatments, CML patients are now given more hope of achieving deep remission and potentially discontinuing medication. A cure for an incurable disease may now be in sight.

Mentioned on this episode: 

• Chronic Myeloid Leukemia (CML)
• Tyrosine Kinase Inhibitors (TKIs)
• FISH test
• Stem Cell Transplant
• Cellular Therapies
• Instilling Hope Through Progress: Myelodysplastic Syndromes (MDS)

Additional LLS Support Resources: 

• Information Specialists 
• Free telephone/web patient programs 
• Free booklets 
• Financial support
• Young Adult Resources
• Survivorship Workbook
• Clinical Trial Support Center
• Online chats 
• Caregiver support 
• LLS Community 
• Support groups 
• Patti Robinson Kaufmann First Connection Program 
• Free Nutrition Consultations

Support for this episode is provided by University of Chicago Comprehensive Cancer Center.

The post Hopeful Advancements for Chronic Myeloid Leukemia (CML) first appeared on The Bloodline with Blood Cancer United Podcast.

Join us as we speak to Laurie Adami, a follicular lymphoma (non-Hodgkin lymphoma) survivor. In this episode, Laurie shares her long journey through multiple cancer treatments, which eventually led to CAR T-cell therapy and complete remission.

Hear one patient’s story of hope, as new treatments continued to come out, keeping her stable until the one that finally worked was approved for her disease. Her story of resilience and determination to stay alive for her young son is the inspiration that so many blood cancer patients need.

Mentioned on this episode: 

Additional LLS Support Resources: 

Support for this episode provided by: Allogene Therapeutics; Bristol Myers Squibb; CRISPR Therapeutics; Janssen Oncology & Legend Biotech; Kite, A Gilead Company; Novartis Oncology.

The post Statistics Don’t Color My Outcome: A CAR T-cell Therapy Success first appeared on The Bloodline with Blood Cancer United Podcast.

Join us as we speak to Dr. Anand Patel and Dr. Satyajit Kosuri from The University of Chicago Medicine about the latest treatment advances for myelodysplastic syndromes (MDS). In honor of MDS Awareness Day on October 25th, the doctors discuss how MDS develops, why genetic mutations matter when choosing a treatment course, and how stem cell transplantation, targeted treatments and cellular therapies bring hope to MDS patients and their families.

Mentioned on this episode: 

• Myelodysplastic syndromes
• Acute Myeloid Leukemia
• Transplant Support and Graft-Versus-Host-Disease (GVHD) episode
• Patient-Doctor Perspectives: Hereditary Myelodysplastic Syndromes (MDS)
• Transplant Optimization Program (TOP)
• MyeloMATCH initiative
• CAR T-cell Therapy
• Stem Cell Transplant
• Cellular Therapies
• Graft-Vs-Host Disease
• Be The Match – Bone Marrow Donor Registry

Additional LLS Support Resources: 

• Information Specialists 
• Free telephone/web patient programs 
• Free booklets 
• Financial support
• Young Adult Resources
• Survivorship Workbook
• Clinical Trial Support Center
• Online chats 
• Caregiver support 
• LLS Community 
• Support groups 
• Patti Robinson Kaufmann First Connection Program 
• Free Nutrition Consultations

Support for this episode is provided by University of Chicago Medicine.

The post Instilling Hope Through Progress: Myelodysplastic Syndromes (MDS) first appeared on The Bloodline with Blood Cancer United Podcast.

Please join us as we speak to Dr. Matthew Davids of Dana-Farber Cancer Institute. In this episode, Dr. Davids discusses current treatments for chronic lymphocytic leukemia (CLL) and the exciting possibilities for the future using immunotherapies.

Dr. Davids shares how the goal of treatment is long term remission and quality of life. Since 2010, BTK Inhibitors, CAR T-cell therapy and other treatments have come on the market and have increased the possibilities for patients to live a long life with CLL.

Mentioned on this episode: 

• Chronic Lymphocyctic Leukemia (CLL)
• How CAR T Cell Therapy Gives Hope to Cancer Patients Podcast Episode
• CURE Magazine Article on CAR T and Young CLL Patients
• American Journal of Managed Care – CAR T cells persist
• Minimal/Measurable Residual Disease (MRD) Fact Sheet
• CAR T-cell Therapy
• CAR T-Cell Therapy Webinar
• How CAR T-Cell Therapy Works In Augmented Reality
• Stem Cell Transplant
• Allogeneic Stem Cell Transplant
• Autologous Stem Cell Transplant
• LLS COVID-19 Resources
• Clinical Trial Support Center
• The Bloodline Subscriber Lounge

Additional LLS Support Resources: 

• Information Specialists
• Financial support
• Free telephone/web patient programs 
• Patti Robinson Kaufmann First Connection Program
• Free booklets 
• Online chats 
• Caregiver support 
• Support groups 
• Free Nutrition Consultations 
• LLS Advocacy
• Survivorship Workbook

Support for this episode provided by BeiGene USA, Inc.; Bristol Myers Squibb; Genentech, Inc. & Biogen; Loxo Oncology at Lilly and Pharmacyclics, An AbbVie Company & Janssen Biotech, and Thomas D. Oxley Fund for CLL Patient Education and Support.

The post Achieving Long-term Remission with Chronic Lymphocytic Leukemia (CLL) first appeared on The Bloodline with Blood Cancer United Podcast.

Please join us as we speak to Dr. Shernan Holtan and guest co-host from LLS, Christina Neilsen. In this episode, Dr. Holtan discusses stem cell transplants; how they work, the different types of transplants, and the side effects, including graft-vs-host disease (GVHD).

Dr. Holtan shares exciting new research on reducing GVHD and provides blood cancer patients with hope as transplantations continue to improve and bring about potential cures.

Mentioned on this episode: 

• Stem Cell Transplant
• Allogeneic Stem Cell Transplant
• Autologous Stem Cell Transplant
• Graft-verses-Host Disease Fact Sheet
• CAR T-cell Therapy
• Clinical Trial Support Center
• Hope Lodge
• Posttransplant Cyclophosphamide
• Be The Match

Additional LLS Support Resources: 

• Information Specialists
• Financial support
• Free telephone/web patient programs 
• Patti Robinson Kaufmann First Connection Program
• Free booklets 
• LLS Public Policy & Advocacy
• Online chats 
• Caregiver support 
• Support groups 
• Free Nutrition Consultations 
• LLS Advocacy
• Survivorship Workbook

The post Let’s Talk About Stem Cell Transplantation: Benefits and Side Effects first appeared on The Bloodline with Blood Cancer United Podcast.

Please join us as we speak to Dr. Daniel Pollyea from the University of Colorado School of Medicine.  In this episode, Dr. Pollyea discusses the group of diseases that make up Myelodysplastic Syndromes (MDS) and how their variability leads to different treatments and prognoses, from active monitoring to chemotherapy and/or stem cell transplantation.  He shares his excitement about new treatment advances and is looking forward to an era of innovative targeted treatments for MDS.

Mentioned on this episode: 

• Myelodysplastic Syndromes (MDS)
• Myelodysplastic Syndromes (MDS) Booklets
• Acute Myeloid Leukemia (AML)
• Stem Cell Transplant
• IPSS-R Scoring System
• IPSS-M Scoring System
• Clinical Trial Support Center

Additional LLS Support Resources: 

• Information Specialists
• Financial support
• Free telephone/web patient programs 
• Patti Robinson Kaufmann First Connection Program
• Free booklets 
• LLS Public Policy & Advocacy
• Online chats 
• Caregiver support 
• Support groups 
• Free Nutrition Consultations 
• LLS Advocacy
• Survivorship Workbook

Support for this episode provided by Taiho Oncology.

The post Myelodysplastic Syndromes (MDS): A Group of Diseases first appeared on The Bloodline with Blood Cancer United Podcast.

Join us as we speak with Charles Huang and Dr. Gabriel Mannis in honor of AML Awareness Day (April 21st). In this episode, Charles tells us about his treatment for AML, participation in clinical trials, and shares about his struggle to find a bone marrow donor as an Asian Pacific Islander. Charles then turned his struggle into legislation to make it easier to join a bone marrow donor registry to save lives. Dr. Mannis, of Stanford Medicine, shares about the latest advances in AML research, from clinical trials in Chimeric Antigen Receptor (CAR) therapy to medications that reduce graft-vs-host disease (GVHD). With research advancing quickly in the field of AML treatment, patients and caregivers are given reasons to have hope after the uncertainty of a diagnosis.

Mentioned on this episode: 

• Acute Myeloid Leukemia
• Myelodysplastic Syndromes (MDS)
• Minimal/Measurable Residual Disease
• CAR T-cell Therapy
• Stem Cell Transplant
• Graft-Vs-Host-Disease (GVHD)
• Charlie’s Law
• Be The Match – Bone Marrow Donor Registry
• LLS Advocacy & Public Policy
• Innovative Therapies in Acute Leukemias podcast episode

Additional LLS Support Resources: 

• Information Specialists
• Free telephone/web patient programs 
• Clinical Trial Support Center
• Free booklets 
• Financial support
• Online chats 
• Caregiver support 
• LLS Community 
• Support groups 
• Free Nutrition Consultations 
• LLS Myeloma Link
• Patti Robinson Kaufmann First Connection Program 
• Young Adult Resources
• Survivorship Workbook

Support for this episode provided by Astellas and Genentech, Inc & Biogen.

The post Patient-Doctor Perspectives: Hope in the Uncertainty of AML first appeared on The Bloodline with Blood Cancer United Podcast.

Join us as we speak to Dr. Hongtao Liu and Dr. Adam DuVall from University of Chicago Medicine, about current and emerging cellular therapies for acute leukemias. These innovative therapies include CAR T-cell therapy, modified Natural Killer (NK) cells and stem cell transplantations. In this episode, we discuss how these groundbreaking therapies have changed the landscape of treatment for acute leukemias. The doctors share what they are excited about in the future, citing how clinical trials are advancing therapies and how cancer centers can better serve the unique needs of adolescent and young adults (AYAs) with acute leukemias by utilizing a holistic and comprehensive approach.

Mentioned on this episode: 

• Acute Lymphoblastic Leukemia
• Acute Myeloid Leukemia
• CAR T-cell Therapy
• Stem Cell Transplant
• Cellular Therapies
• Minimal/Measurable Residual Disease (MRD)
• Graft-Vs-Host Disease
• Adolescent and Young Adult (AYA) Oncology Program at University of Chicago
• CALMM Clinic at University of Chicago
• Young Adult Resources
• Survivorship Workbook
• Between Two Kingdoms

Additional LLS Support Resources: 

• Information Specialists 
• Free telephone/web patient programs 
• Free booklets 
• Financial support
• Clinical Trial Support Center
• Online chats 
• Caregiver support 
• LLS Community 
• Support groups 
• Patti Robinson Kaufmann First Connection Program 
• Free Nutrition Consultations

Support for this episode is provided by University of Chicago Medicine.

The post Innovative Therapies for Acute Leukemias first appeared on The Bloodline with Blood Cancer United Podcast.

Join us as we speak to Dr. Peter Riedell and Dr. Benjamin Derman from University of Chicago Medicine, about the latest research coming out of the annual meeting of the American Society of Hematology (ASH). In this episode, we discuss new treatments on the horizon for lymphoma and myeloma. The doctors share how innovative therapies such as CAR T-cell therapy and new combinations of medicines are showing significant promise, providing further hope to patients.

Mentioned on this episode: 

• Lymphoma
• Myeloma
• Amyloidosis
• MGUS (Monoclonal Gammopathy of Undetermined Significance)
• Smoldering myeloma (Myeloma staging)
• Minimal/Measurable Residual Disease (MRD)
• Bispecific Antibody Therapy
• ASH Annual Meeting Highlights
• Anxiety and Hope: Living with CLL podcast episode
• Dara-KRd
• CAR T-cell Therapy
• Stem Cell Transplant
• Graft-Vs-Host Disease

Additional LLS Support Resources: 

• Information Specialists 
• Free telephone/web patient programs 
• Free booklets 
• Financial support
• Clinical Trial Support Center
• Online chats 
• Young Adult Resources
• Caregiver support 
• LLS Community 
• Support groups 
• Patti Robinson Kaufmann First Connection Program Free Nutrition Consultations

Support for this episode is provided by University of Chicago Medicine.

The post Emerging Research in Lymphoma and Myeloma first appeared on The Bloodline with Blood Cancer United Podcast.

Join us as we speak to Dr. Brady Stein, a clinical hematologist and researcher at the Northwestern University Feinberg School of Medicine in Chicago, IL. In this episode, Dr. Stein discusses the rare blood cancer, myelofibrosis (MF), which is a type of myeloproliferative neoplasms (MPNs). Hear about the unique characteristics of MF, how it develops, and the current and emerging treatments that give MF patients hope.

Mentioned on this episode: 

• Myelofibrosis
• Myeloproliferative Neoplasms
• ASH (American Society of Hematology)
• Pushing for a Diagnosis: A Polycythemia Vera (PV) Story
• Clinical Trial Support Center

Additional LLS Support Resources: 

• Information Specialists 
• Free telephone/web patient programs 
• Free booklets 
• Financial support
• Online chats 
• Caregiver support 
• LLS Community 
• Support groups 
• Patti Robinson Kaufmann First Connection Program 
• Free Nutrition Consultations 
• LLS Advocacy
• LLS Myeloma Link

Support for this episode provided by AbbVie.

The post Under the MPN Umbrella: Exploring Myelofibrosis first appeared on The Bloodline with Blood Cancer United Podcast.