The researchers found that taurine suppressed age-associated weight gain in female mice (even in “menopausal” mice), increased energy expenditure, increased bone mass, improved muscle endurance and strength, reduced depression-like and anxious behaviors, reduced insulin resistance, and promoted a younger-looking immune system, among other benefits.

“Not only did we find that the animals lived longer, we also found that they’re living healthier lives,” Yadav says.

#taurine #aging #health

Singh, P., Gollapalli, K., Mangiola, S., Schranner, D., Yusuf, M. A., Chamoli, M., Shi, S. L., Bastos, B. L., Nair, T., Riermeier, A., Vayndorf, E. M., Wu, J. Z., Nilakhe, A., Nguyen, C. Q., Muir, M., Kiflezghi, M. G., Foulger, A., Junker, A., Devine, J., . . . Yadav, V. K. (2023). Taurine deficiency as a driver of aging. Science. https://doi.org/abn9257

Taurine, serum concentration, aging, anti-aging, disease, hypotaurine, type 2 diabetes, wbc, insulin, bmi. Metabolism, waist circumference, N-acetyl taurine, exercise, hemoglobin, platelets, circulating taurine, age-associated pathologies, lower glucose

Taurine and a Longer, Healthier Life #taurine #hypotaurine #stem #aging #health #longlife #endurance #strength #youthfulskin #nacetyltaurine #antiaging

Frailty and Flavonols Episode 1141 JUN 2023

Frailty and Flavonols

Other subclasses showed no association (P values range: 0.12–0.99), but every 10 mg/d of higher quercetin intake was associated with 35% lower odds of frailty onset (OR: 0.65; 95% CI: 0.48–0.88).

#Frailty #quercetin #flavonols

Oei, S., Millar, C. L., Nguyen Lily, T. N., Mukamal, K. J., Kiel, D. P., Lipsitz, L. A., Hannan, M. T., & Sahni, S. (2023). Higher intake of dietary flavonols, specifically dietary quercetin, is associated with lower odds of frailty onset over 12 years of follow-up among adults in the Framingham Heart Study. The American Journal of Clinical Nutrition. https://doi.org/10.1016/j.ajcnut.2023.04.013

Frailty, falling, weakness, quercetin, flavonols, osteoporosis, sarcopenia. kaempferol , myricetin, aging, elderly, fisetin, strength, balance

Frailty and Flavonols Episode 1141 JUN 2023

Other subclasses showed no association (P values range: 0.12–0.99), but every 10 mg/d of higher quercetin intake was associated with 35% lower odds of frailty onset (OR: 0.65; 95% CI: 0.48–0.88).

#Frailty #quercetin #flavonols

Oei, S., Millar, C. L., Nguyen Lily, T. N., Mukamal, K. J., Kiel, D. P., Lipsitz, L. A., Hannan, M. T., & Sahni, S. (2023). Higher intake of dietary flavonols, specifically dietary quercetin, is associated with lower odds of frailty onset over 12 years of follow-up among adults in the Framingham Heart Study. The American Journal of Clinical Nutrition. https://doi.org/10.1016/j.ajcnut.2023.04.013

Frailty, falling, weakness, quercetin, flavonols, osteoporosis, sarcopenia. kaempferol , myricetin, aging, elderly, fisetin, strength, balance

The MIT group is not the first to show that gamma frequency tactile stimulation can affect brain activity and improve motor function, but they are the first to show that the stimulation can also reduce levels of the hallmark Alzheimer’s protein phosphorylated tau, keep neurons from dying or losing their synapse circuit connections, and reduce neural DNA damage.

#Vibrotactile #Alzheimers #tau

Suk, H., Buie, N., Xu, G., Banerjee, A., Boyden, E. S., & Tsai, L. (2023). Vibrotactile stimulation at gamma frequency mitigates pathology related to neurodegeneration and improves motor function. Frontiers in Aging Neuroscience, 15. https://doi.org/10.3389/fnagi.2023.1129510

Neurodegenerative, dementia, Alzheimer’s, tau, somatosensory cortex, primary motor cortex, motor function, gamma frequency, 40hz, Vibrotactile stimulation, GENUS, for Gamma Entrainment Using Sensory stimuli, als, ftd, Pick disease, progressive supranuclear palsy, tauopathies, frontotemporal dementia, Parkinson’s disease

Gamma Frequency clears brain debris and improves motor function #40hz #vibrotactile #stem #neurodegenerative #dementia #tau #alzheimer #cortex #brain

The MIT group is not the first to show that gamma frequency tactile stimulation can affect brain activity and improve motor function, but they are the first to show that the stimulation can also reduce levels of the hallmark Alzheimer’s protein phosphorylated tau, keep neurons from dying or losing their synapse circuit connections, and reduce neural DNA damage.

#Vibrotactile #Alzheimers #tau

Suk, H., Buie, N., Xu, G., Banerjee, A., Boyden, E. S., & Tsai, L. (2023). Vibrotactile stimulation at gamma frequency mitigates pathology related to neurodegeneration and improves motor function. Frontiers in Aging Neuroscience, 15. https://doi.org/10.3389/fnagi.2023.1129510

Neurodegenerative, dementia, Alzheimer’s, tau, somatosensory cortex, primary motor cortex, motor function, gamma frequency, 40hz, Vibrotactile stimulation, GENUS, for Gamma Entrainment Using Sensory stimuli, als, ftd, Pick disease, progressive supranuclear palsy, tauopathies, frontotemporal dementia, Parkinson’s disease

Gamma Frequency clears brain debris and improves motor function #40hz #vibrotactile #stem #neurodegenerative #dementia #tau #alzheimer #cortex #brain

Ear acupuncture with beads may help shed the pounds Episode 1139 MAY 2023

The study found substantial differences after 3 months, with participants losing on average 10.4cm off their waist circumference (from an average 98.4cm at the start of the study to 88cm) and 4% of total body fat (from average 28.2% to 24.3%).

#auricular #ear #weightloss

Poster presentation PO4.085 at the European Congress on Obesity (ECO) Dublin, Ireland (17-20 May 2023)

Auricular, ear, acupuncture, acupressure, appetite, metabolism, weight loss, bmi, hunger, digestion, vagus nerve, beads, acupoint stimulation

Ear acupuncture with beads may help shed the pounds #ear #stem #auricular #acupuncture #acupressure #weightloss #bmi #vagusnerve #metabolism

Ear acupuncture with beads may help shed the pounds. Episode 1139 MAY 2023

The study found substantial differences after 3 months, with participants losing on average 10.4cm off their waist circumference (from an average 98.4cm at the start of the study to 88cm) and 4% of total body fat (from average 28.2% to 24.3%).

#auricular #ear #weightloss

Poster presentation PO4.085 at the European Congress on Obesity (ECO) Dublin, Ireland (17-20 May 2023)

Auricular, ear, acupuncture, acupressure, appetite, metabolism, weight loss, bmi, hunger, digestion, vagus nerve, beads, acupoint stimulation

Ear acupuncture with beads may help shed the pounds #ear #stem #auricular #acupuncture #acupressure #weightloss #bmi #vagusnerve #metabolism

The manipulation of the timing and dose of kiwifruit may

#kiwi #exercise #sleep

Doherty, R., Madigan, S., Nevill, A., Warrington, G., &

Kiwi, kiwifruit, sleep, Actinidia Deliciosa,  training, recovery, disturbed sleep, anxiety ,

Kiwi Fruit Improved Sleep and Recovery Episode 1138 MAY 2023

The manipulation of the timing and dose of kiwifruit may

#kiwi #exercise #sleep

Doherty, R., Madigan, S., Nevill, A., Warrington, G., &

Kiwi, kiwifruit, sleep, Actinidia Deliciosa,  training, recovery, disturbed sleep, anxiety ,

Kiwi Fruit Improved Sleep and Recovery Episode 1138 MAY 2023

Brain Energy and Function, Improved with Glycine/NAC? Episode 1137 MAY 2023

The results of this study provide proof-of-concept that GlyNAC supplementation improves age-associated cognitive decline and supports brain health in aging by improving/correcting brain GSH deficiency, elevated OxS, mitochondrial dysfunction, abnormal mitophagy and autophagy, inflammation, impaired glucose transport/uptake, elevated genomic damage, and reversing the decline in brain neurotrophic growth factors. GlyNAC could be a simple and effective nutritional supplement to support brain health and cognitive function in aging, and warrants additional investigation.

#glynac #brainrespiration #cognition

Kumar, P., Osahon, O. W., & Sekhar, R. V. (2023). GlyNAC (Glycine and N-Acetylcysteine) Supplementation in Old Mice Improves Brain Glutathione Deficiency, Oxidative Stress, Glucose Uptake, Mitochondrial Dysfunction, Genomic Damage, Inflammation and Neurotrophic Factors to Reverse Age-Associated Cognitive Decline: Implications for Improving Brain Health in Aging. Antioxidants, 12(5), 1042. https://doi.org/10.3390/antiox12051042

Glynac, glycine, N-Acetylcysteine, correction, GSH Synthesis , cognitive improvement, brain health, GSH, OxS, mitochondrial energetics, autophagy/mitophagy, glucose transporters, inflammation, genomic damage, neurotrophic factors

Brain Energy and Function, Improved with Glycine/NAC? Episode 1137 MAY 2023 #glynac #glycine #nacetylcysteine #brain #aging #brainheath #stem