Coronavirus Central

Episode Six of Coronavirus Central looks much more deeply into the ACE-II pathway by which Covid infects humans and what implications result.  We start by examining the nature of the Angiotensin Converting Enzyme, revealing it is an essential component of all humans with heavy clusters in the lower respiratory system, and being used to regulate blood pressure.  As we review news and studies based both on Covid and SARS which uses this same mechanism, we learn of the threat not just from infection, but from reinfection where the immune system may begin attacking our own cardiovascular function when it tries to fight off this virus, in a cytokine storm similar to what happened with the Spanish Flu.   Considering this two-tier threat to public health, we consider the potential that Covid could be a bioweapon in light of certain actions by the PLA and a troubling document that suggests at least some people in China were made aware of this threat weeks before the general public.

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Latest statistics: https://covid19info.live/

Angiotensin Converting Enzyme definition: https://en.wikipedia.org/wiki/Angiotensin-converting_enzyme

Tissue distribution of ACE: https://www.ncbi.nlm.nih.gov/pubmed/15141377

Risks to kidney and testis health from Covid:  https://www.medrxiv.org/content/10.1101/2020.02.12.20022418v1

Reinfection Worse?: https://www.taiwannews.com.tw/en/news/3876197

Chinese military taking over Wuhan lab: https://www.dailymail.co.uk/news/article-8003713/China-appoints-military-bio-weapon-expert-secretive-virus-lab-Wuhan.html

Document showing earlier quarantine for PLA university: https://twitter.com/jenniferatntd/status/1228435515776667649China stopping use of paper money: https://www.bloomberg.com/news/articles/2020-02-15/china-quarantines-cash-to-sanitize-old-bank-notes-from-virus

In Episode 5, we review a study that suggests a far higher case count in Wuhan than previously reported by using statistics to determine both the number of asymptomatic carriers as well as to offer analysis of how effective the quarantine efforts are proving.   From there, we look at the potential for re-infection as well as how this disease might evolve and recur on a seasonal basis.  A deeper dive into the supply line reveals the many vulnerabilities in public health against an outbreak including pharmaceuticals, medical supplies, hospital beds, and production capacity.  We take a first glimpse at a potential effort to protect first responders and most vulnerable populations with antibody production as well.

Join the Telegram chat at: https:/t.me/coronaviruscentral.comFacebook: @coronaviruscentralTwitter: @coronaviruscastLinks:

Latest statistics: https://covid19info.live/

Transmission Study: https://www.medrxiv.org/content/10.1101/2020.02.12.20022434v1

Long-term Covid Scenarios: https://www.statnews.com/2020/02/04/two-scenarios-if-new-coronavirus-isnt-contained/

In Episode Four, we review the change in criteria by the Chinese government to include clinically diagnosed cases which saw a jump of 14,480 new cases and 242 new deaths reported on February 12th.  These new criteria bring the numbers closer to what mathematical modeling predicts as we share two studies that suggest the transmission rate should be between 5 and 6 with an incubation period as long as 24 days observed.  This means the 14 day quarantines are ineffective, as the spread of cases into the Philippines, Singapore, Thailand, Vietnam, and others makes clear, from which global air and trade continues unabated.  We close with a tip about how to ensure you always have potable drinking water for a $5 investment.Join the Telegram chat at: https:/t.me/coronaviruscentral.comFacebook: @coronaviruscentralTwitter: @coronaviruscastLinks:

Latest statistics: https://covid19info.live/

Change in reporting for Chinese cases in Hubei: http://www.xinhuanet.com/english/2020-02/13/c_138779875.htm

Study supporting increase infectivity rate: https://www.medrxiv.org/content/10.1101/2020.02.07.20021154v1

24 day incubation period found: https://www.straitstimes.com/asia/east-asia/research-shows-3-day-median-incubation-period-for-coronavirusWHO has no plans to change quarantine protocol: https://www.straitstimes.com/singapore/health/coronavirus-no-change-to-recommended-quarantine-despite-study-suggesting-24-dayRegional quarantines in Vietnam: https://www.bangkokpost.com/world/1856784/vietnam-quarantines-area-with-10-000-residents-over-coronavirusGrowing cases in the Philippines: https://www.cnnphilippines.com/news/2020/2/12/59-coronavirus-case-contacts-flu-like-symptoms.htmlThailand reports stable case load: https://www.bangkokpost.com/thailand/general/1856074/local-virus-cases-stable-at-33Current airline restrictions: https://www.thejakartapost.com/travel/2020/02/07/airlines-suspend-china-flights-due-to-coronavirus-outbreak.htmlHow to purify water with bleach concentrate: https://sunplay.com/blogs/posts/purify-water-with-pool-shock

In Episode Three of Coronavirus Central, we're going to review the daily numbers, take a much closer look at Singapore's situation as a larger example that parallels the issues the cruise ship are facing, explain the difference between mortality rate and case fatality rate and also why lower initial mortality can with a highly infectious virus make it harder to stop, trace, leading to more deaths in the end.  An introduction to some US government resources is also shared, as well as information about coconut oil as a potential natural option to bolster your own defenses against Covid-19.Straits Times Article as Singapore Reaches 50 Cases: https://www.straitstimes.com/singapore/health/coronavirus-3-new-cases-in-singapore-2-from-grace-assembly-of-god-church-1-from-dbs

Why Higher CFR Isn't Always Good: https://medium.com/@newapollo/novel-coronavirus-case-fatality-rate-is-no-reason-for-optimism-a4a921858543

Pandemic and All Hazards Preparedness and Reauthorization Act of 2013: https://en.wikipedia.org/wiki/Pandemic_and_All-Hazards_Preparedness_Reauthorization_Act_of_2013

Potential for Coconut Oil Against NCov-19: https://www.icp.org.ph/2020/01/the-potential-of-coconut-oil-and-its-derivatives-as-effective-and-safe-antiviral-agents-against-the-novel-coronavirus-ncov-2019/

In Episode 2 of the Coronavirus Central Podcast, we report the daily statistics, feature an update of the  reasons why so many people dispute the official numbers being provided to the WHO by the Chinese Government, offer a closer look at the case of the quarantined cruise ship "Diamond Princess" that now has 135 reported cases, and examine the wider economic implications.  A detailed discussion of the dependency of the international consumer market on Chinese pharmaceuticals is considered, and considering that the vast majority of generic drugs including nearly all antibiotics, as well as most of the core ingredients come from China, it is likely that by the end of February, we will see major medical shortages of key medication worldwide due to the global supply chain.  Alternatives to traditional medicine are briefly considered.

Miles Guo Interview with Steve Bannon: https://www.youtube.com/watch?v=2WyfVnL5_AMDr. John Campbell on Most Current Lethality Rates: https://www.youtube.com/watch?v=6HCRmTHCUaoChinese Central Bank Injecting Liquidity: http://www.xinhuanet.com/english/2020-02/10/c_138770000.htmUS Dependence on Chinese Pharmaceuticals: https://www.cfr.org/blog/us-dependence-pharmaceutical-products-china

In Episode One of the Coronavirus Central Podcast, we introduce the purpose of our podcast and how we hope to structure future episodes to provide daily information about breaking news, the latest numbers, relevant studies, on the ground information, and how to prepare.This episode features a basic introduction and background for the outbreak, what the novel coronavirus is, a crash course in the relevant virology, and a few basic preparation.  We also look more deeply into the study from the Journal of American  Medicine  from February 7,  2020 that reviewed 138 cases from Wuhan.JAMA Study: https://jamanetwork.com/journals/jama/fullarticle/2761044Join Us on Telegram: https://t.me/coronaviruscentral