White House Coronavirus Response Coordinator Dr. Ashish Jha joins Dr. Marc Siegel and discusses where we stand with SARS CO-V-2, the benefits of getting the updated COVID-19 booster AND a flu shot at the same time, Long COVID, and Paxlovid.

Decorated Public Health expert Admiral Brett Giroir joins Dr. Marc Siegel to discuss President Biden's recent COVID diagnosis, treatment and outlook. Hear how he thinks vaccines, testing and treatment have evolved since the onset of the pandemic.

Member of the FDA's Vaccines and Related Biological Products Advisory Committee (VRBPAC), Dr. Paul Offit, joins Dr. Marc Siegel and offers insight into the group’s decision to recommend approval of the COVID vaccine for children as young as 6 months.

NIAID Director and Chief Medical Advisor to the President, Dr. Anthony Fauci joins Dr. Marc Siegel and discusses COVID variants, vaccines and boosters, COVID fatigue and public health precautions, Long COVID, Paxlovid rebound, Monkeypox, and the responsibility of every individual to reject the normalization of untruths.

Commissioner of Food and Drugs at the FDA Dr. Robert M. Califf joins Dr. Marc Siegel and discusses the changing narrative on Covid19 vaccines and their importance, the role of Paxlovid in treating Covid19, the overdose epidemic, and why he believes misinformation is the leading cause of death.

Director of the Vaccine and Immunotherapy Center (VIC) at Massachusetts General Hospital, Dr. Mark Poznansky, joins Dr. Marc Siegel and discusses the latest information on vaccine development, current therapeutics, Long COVID, individual responsibility in preventing the spread of COVID, and the United States’ ability to tackle the next pandemic.

Dr. Steve Hodak and his guest, Dr. Leopoldo Segal, discuss current therapeutics and our ability to treat severe cases in the ICU. They also discuss promising new research into ACE2 inhibitors and what the findings can mean for the future of treating and preventing severe virus infection.

21st Surgeon General of the United States, Dr. Vivek Murthy joins Dr. Marc Siegel and discusses what’s going on with Omicron and other COVID 19 variants in the US, pandemic protocols, and masking on planes. He also addresses the mental health crisis and opioid epidemic.

Public Health Professor at George Washington University and Former Health Commissioner of Baltimore, Dr. Leana Wen joins Dr. Marc Siegel and discusses her reporting on Long COVID, the Gridiron outbreak of COVID-19, the second booster and who should receive it, how we can protect against the virus, and funding for future pandemics.

Founding Director of The UAB Travelers Health Clinic, Dr. David Freedman, joins Dr. Ira Breite and discusses guidelines for traveling abroad, testing requirements for travel, and what to expect if you get a COVID infection when you’re in a foreign country.