Septic shock is one of the most common causes of deaths in critically ill patients. The updated Surviving Sepsis Campaign Guidelines provide recommendations on the use of adjunct steroids in the treatment of sepsis. However, when to start corticosteroids is still unknown – or is it? This episode of GameChangers evaluates the timing of corticosteroid use in sepsis.

The GameChanger
Corticosteroids are now recommended by the Surviving Sepsis Campaign Guidelines in septic shock patients receiving pressors. Early initiation of corticosteroids has now been associated with decreased ICU length of stays and time on pressors.

 Show Segments
00:00 – Introductions 
01:25 – Corticosteroids in Septic Shock 
04:47 – Initiation of Corticosteroids
14:57 – The GameChanger 
19:24 – Closing Remarks 

 Host
Geoff Wall, PharmD., BCPS, FCCP, CGP
Professor of Pharmacy Practice, Drake University
Internal Medicine/Critical Care, UnityPoint Health

 Dr. Wall is a member of the Janssen Speaker's Bureau.

References and Resources
Comparison of Early Versus Late Initiation of Hydrocortisone in Patients with Septic Shock in the ICU Setting

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 CE Information

 Learning Objectives

Upon successful completion of this knowledge-based activity, participants should be able to:

1. Identify ideal timing of corticosteroids use in septic shock patients
 2. Discuss the dosing recommendations of corticosteroids in septic shock patients

0.05 CEU | 0.5 Hrs
ACPE UAN: 0107-0000-22-168-H01-P
Initial release date: 04/18/22
Expiration date: 04/18/2023
Additional CPE and CME details can be found here.

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