The rapidly spreading omicron variant is now the dominant Covid strain in the U.S., representing 73% of sequenced cases, according to data published today by the Centers for Disease Control and Prevention. CDC Director Dr. Rochelle Walensky joins Shep Smith to discuss the spread of omicron among new Covid cases in the U.S. and what families can do to protect themselves over the holiday season. CNBC’s Meg Tirrell reports on what we can look forward to in the world of medicine in 2022. CNBC’s Jabari Young discusses the number of professional athletes who have been added to Covid lists, and what the leagues are hoping to do about it. NBC’s Sahil Kapur reports on Sen. Joe Manchin’s refusal to support President Joe Biden’s Build Back Better plan, and Majority Leader Chuck Schumer’s vow to bring the bill to a vote in early January. Former presidential candidate Andrew Yang discusses his efforts to create a third political party in the United States. Plus, CNBC’s Perry Russom reports on why families around the country are struggling to afford diapers for their kids.