Rob Mac Sweeney discusses the ACIOS study with Tim Baker, the study lead. ACIOS is a point prevalence study describing the burden of critical illness in Africa. It was published in the Lancet in March, 2025.

Rob Mac Sweeney discusses the IVIO trial with investigators Lars Wiuff Andersen and Mikael Fink Valentine from Aarhus, Denmark. The IVIO trial compared intraosseous with intravenous vascular access in adult patients suffering an out-of-hospital cardiac arrest. It was presented at the 2024 European Resuscitation Council congress in Athens and simultaneously published in the New England Journal of Medicine.

Rob Mac Sweeney discusses the PARAMEDIC 3 trial with it's investigators Keith Couple and Ranjit Lall from the University of Warwick, England. PARAMEDIC 3 compared intravenous with intraosseous vascular access in adult patients suffering cardiac arrest and requiring drug administration during ongoing resuscitation. It was presented at the European Resuscitation Council meeting in Athens on October 31st and simultaneously published in the New England Journal of Medicine.

Rob Mac Sweeney chats with Jessica Spence about the B-FREE trial, investigating benzodiazepine-free anaesthesia for the prevention of delirium in cardiac surgery

Bala Venkatesh (Brisbane) hosts a panel discussion entitled "Beyond Platform Trials" at the Critical Care Reviews Meeting 2023. The panellists include Bronagh Blackwood (Belfast), Susan Rowell (Chicago), Fernando Zampieri (Edmonton), Marion Campbell (Aberdeen), David Harrison (London), Roger Lewis (Los Angeles), Derek Angus (Pittsburgh) & Kathy Rowan (London).

Kathy Rowan (London) hosts a fascinating panel discussion on causality at the Critical Care Reviews Meeting 2023. The panellists include Bronwen Connolly (Belfast), Ewan Goligher (Toronto), Flavia Machado (Sao Paulo), Kath Maitland (Kalifi), John Norrie (Edinburgh), Victoria Cornelius (London), Andrew Althouse (Pittsburgh) and Chris Seymour (Pittsburgh).

Dr Lisa Higgins (Melbourne) presents the long term outcomes of the REMAP-CAP domains at the Critical Care Reviews Meeting 2023. Prof Howard Bauchner (Boston) delivers an editorial. Prof Christopher Seymour (Pittsburgh) chairs the session.

Nina Christine Andersen-Ranberg presents the AID-ICU trial, investigating haloperidol for the management of delirium in the ICU. Danny McAuley delivers an editorial. Anders Perner joins the discussion and the session is chaired by Paul Mouncey.

Prof Flavia Machado (Sao Paulo) delivers the John Hinds Lecture at the Critical Care Reviews Meeting 2023, describing the story of BRICNET, the Brazilian Critical Care Trials Group. The session commences with Dr Chris Nutt remembering our friend, Dr John Hinds.

You're listening to the audio version of the PROCOAG trial presentation from the Critical Care Reviews Meeting 2023. The PROCOAG trial investigated the efficacy and safety of early administration of 4-factor prothrombin complex concentrate in trauma patients at risk of massive transfusion. The trial is presented by Pierre Bouzat from Grenoble. Susan Rowell from Chicago, delivers the editorial. The session is chaired by Chris Seymour (Pittsburgh). PROCOAG was published in JAMA in March 2023.