In this seminar, the last in my series of four on glocalisation, I discuss the three different ways that headquarters and affiliates learn from each other to improve the adaptation of global strategies to local markets.

I’d welcome comments and if you find this useful, please share it with your colleagues. If you would like to read the article on which this seminar is based, you can request at www.pragmedic.com (my latest publications). If you would like to browse over 300 articles about the evolution of business models and strategy in the life sciences industry, take a look at www.pragmedic.com, my published work. If you'd like to follow my research in this area, follow at LinkedIn (@drbriandsmith) and Twitter (@profbriandsmith) If, like me, you're fascinated by our industry and would like to set up an informal, virtual chat with me then get in touch through www.pragmedc.com. And of course I'd love it if you shared, liked and subscribed to both my Darwin's Medicine podcast and my YouTube channel.

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In this seminar, I discuss how, as firms evolve, they pass points of no return so that they are no longer capable of what they used to be good at.

This seminar describes the lessons learned from a deep-dive workshop about how to adapt to the Inflation Reduction Act's measures to control drug prices in the US, but it is equally relevant for any pharma or medtech company trying to influence market access or reimbursement policy.

If you've worked in pharma, medtech or other life sciences sectors for any length of time, you will probably have been frustrated by the the caution and sometimes risk aversion of its leaders and its investors.

In this seminar, I'll give an evolutionary explanation of why our industry is so cautious, an explanation that will help you and your colleagues seize more opportunities.

I’d welcome comments and if you find this useful, please share it with your colleagues. If you would like to read the article on which this seminar is based, you can request at www.pragmedic.com (my latest publications). If you would like to browse over 300 articles about the evolution of business models and strategy in the life sciences industry, take a look at www.pragmedic.com, my published work. If you'd like to follow my research in this area, follow at LinkedIn (@drbriandsmith) and Twitter (@profbriandsmith) If, like me, you're fascinated by our industry and would like to set up an informal, virtual chat with me then get in touch through www.pragmedic.com.And of course I'd love it if you shared, liked and subscribed to both my Darwin's Medicine podcast and my YouTube channel.

The answer to this may not be what you think and may be found in your thymus.

If you would like the article on which this seminar is based, you can request it at www.pragmedic.com

I’d welcome comments and if you find this useful, please share it with your colleagues. If you would like to read the article on which this seminar is based, you can request at www.pragmedic.com (my latest publications). If you would like to browse over 300 articles about the evolution of business models and strategy in the life sciences industry, take a look at www.pragmedic.com, my published work. If you'd like to follow my research in this area, follow at LinkedIn (@drbriandsmith) and Twitter (@profbriandsmith) If, like me, you're fascinated by our industry and would like to set up an informal, virtual chat with me then get in touch through www.pragmedc.com.And of course I'd love it if you shared, liked and subscribed to both my Darwin's Medicine podcast and my YouTube channel.

If you would like to read the full length article on which this seminar is based, you can request at www.pragmedic.com (my latest publications).

I’d welcome comments on this video and if you find it useful, please share it with your colleagues. If you would like to browse over 300 articles about the evolution of business models and strategy in the life sciences industry, take a look at www.pragmedic.com, my published work. If you'd like to follow my research in this area, follow at LinkedIn (@drbriandsmith) and Twitter (@profbriandsmith) If, like me, you're fascinated by our industry and would like to set up an informal, virtual chat with me then get in touch through www.pragmedic.com.And of course I'd love it if you shared, liked and subscribed to both my Darwin's Medicine podcast and my YouTube channel.

But it's since become debased and many now apply the term to any minor, incremental change.

In this seminar, you'll learn what disruptive innovation is, what it isn't and the conditions that lead to it happening.

I’d welcome comments and if you find this useful, please share it with your colleagues. If you would like to read the article on which this seminar is based, you can request at www.pragmedic.com (my latest publications). If you would like to browse over 300 articles about the evolution of business models and strategy in the life sciences industry, take a look at www.pragmedic.com, my published work. If you'd like to follow my research in this area, follow at LinkedIn (@drbriandsmith) and Twitter (@profbriandsmith) If, like me, you're fascinated by our industry and would like to set up an informal, virtual chat with me then get in touch through www.pragmedc.com.And of course I'd love it if you shared, liked and subscribed to both my Darwin's Medicine podcast and my YouTube channel.