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Explosions have again been heard in locations across Tehran, as darkness fell in Iran's capital. Earlier the United States and Israel stepped up their attacks on Iranian cities, including Karaj and Isfahan, where eyewitnesses described bodies lying in the street. Also, President Trump has said he needs to be personally involved in selecting Iran's next leader. Also in the programme: US Secretary of Homeland Security Kristi Noem is replaced; and how to recognise a real Stradivarius. (Photo: A view of the Azadi sports complex after the airstrikes in Tehran, Iran, 05 March 2026. CREDIT: ABEDIN TAHERKENAREH/EPA/Shutterstock)

The United States and Israel have carried out a sixth day of attacks. Columns of smoke are towering in the sky in the capital, Tehran, where the Azadi football stadium appears to have been severely damaged. We'll also investigate unconfirmed reports that the US is trying to foment a Kurdish rebellion in the north of Iran.Also in the programme: people in Nepal have been voting for the first time since last year's "Gen Z" demonstrations, in which dozens of young protesters died; and the drug trials that have had some terrific results for children with the severest epilepsy.(Photo: People gather on the sides of a road as smoke rises in the background following an explosion, amid the U.S.-Israeli conflict with Iran, in Tehran, Iran, March 5, 2026. Credit: Majid Asgaripour/West Asia News Agency via REUTERS)

US Secretary of Defense Pete Hegseth has said an American submarine sank an Iranian warship in the Indian Ocean.Washington says it's the first time since the Second World War it's used a torpedo to sink an enemy vessel.Also on the programme: we gauge the scale of the attacks inside Iran by speaking to a resident in Tehran and verifying video footage; and a look at a new AI model, trained on the DNA of over 100,000 species, that is capable of designing new genomes.(Photo: US Defence Secretary Pete Hegseth speaks during a press briefing at the Pentagon on 2 March. Credit: EPA/Shutterstock)

The Sri Lankan navy says it has rescued 32 people after a distress call from the Iranian IRIS Dena, with around 140 people on board currently missing. We also hear from Iraq's Kurdistan region where reports suggest the US could back the Kurdish armed groups to cross over into Iran in a ground operation.Also on the programme: the latest from the onflict in the Middle East, with a lineup of who is in the running to take over from Iran's Supreme Leader; the controversial 'Moonies' church that has contravened the law in Japan, and proof that a woman's brain does change during pregnancy. (Photo: Iranian warship IRIS Dena is seen in the Bay of Bengal during International Fleet Review held at Visakhapatnam in India on 18 February, 2026. Credit: Associated Press)

President Trump says both Iran's leadership and military have been knocked out by US and Israeli attacks on day four of the war. We'll bring you the latest and hear from Lebanon's Deputy Prime Minister as Israel pursues the Iran-backed Hezbollah militia; and how might Gulf states react if Iran continues to attack them?(An explosion in Tehran, Iran as US/Israeli attacks continue. Credit: EPA/Shutterstock)

As loud explosions continue to be heard across Tehran there are reports that many residents are trying to flee the capital by car while others are stocking up on essential supplies. Israel says it's bombed Iran's presidential office and the US claims to have destroyed command facilities and missile launch sites across the country. Iran has threatened to open the gates of hell as it retaliates.Also, Leaked photo, hot tub, and Pizzagate - video of Clintons' testimony on Epstein ties released. And discovering your old painting was actually a masterpiece by Rembrandt!(Photo: A street in Tehran this morning following a blast at a police station. Credit: Reuters)

President Donald Trump says the US continues to carry out "large-scale combat operations" in Iran to eliminate threats posed by the Iranian regime. As explosions thunder across the Iranian capital, we'll hear from a journalist in Tehran. Also on the programme: the conflict spreading into Lebanon and across the Gulf, and why one Trump-supporting American commentator believes this war of choice was a mistake. (Photo: President Donald Trump attends a Medal of Honor ceremony at the White House in Washington, DC. Credit: Reuters)

We hear from Lebanon and head to the Persian Gulf to take a look at the impact on oil prices. Israel's Head of State, President Isaac Herzog speaks to the BBC about his perspective on the conflict. Also on the programme: we hear about the British allied response to the war as Cyprus remains on high alert and Greece sends military vessels and aircraft to help. (Photo: Aftermath of an Israeli & US strike in Gandhi Hotel Hospital in Tehran Credit: Majid Asgaripour/West Asia News Agency via Reuters)

Israel has said it has dealt a "severe blow" to Iran's command and control centres as it continues to strike the country. Iran's retaliations have led to casualties across the region. In the meantime, President Trump has said he is open to talking to Iran's new interim leaders.We hear the latest from the ground in Tehran, talk to an Israeli MP and an economist about the impact on oil prices as shipping comes to a standstil in the Strait of Hormuz. (Photo: a supporter of deceased Iranian Supreme Leader Ayatollah Ali Khameini holds its picture at a rally in Lebanon. Credit: EPA/Shutterstock)

Iran's interim leadership council has been named following the death of its Supreme Leader Ayatollah Ali Khamenei in a US-Israel attack. In Israel nine people have been killed by retaliatory strikes from Tehran.(Photo: Smoke rises following an explosion, after Israel and the U.S. launched strikes on Iran, in Tehran, Iran, March 1, 2026. CREDIT: Majid Asgaripour/WANA (West Asia News Agency) via REUTERS)