Deadpool is joining the MCU, but will he be immortal / un-killable as he was in the Fox X-Men universe?

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How do you kill Deadpool permanently, and does that make Wade Wilson "immortal"? What exactly is the difference between immortality and invulnerability in the Marvel universe? In this episode of Big Question, Erik Voss and Tommy Bechtold dive deep into the mystery of Deadpool's immortality curse, how it connects to Thanos and Lady Death, and how that could be adapted to the rules of the MCU. Where do Avengers go where they die? Will Deadpool exist in the Ancestral Plane, the Orange Soul Realm, or the Quantum Realm, before he joins the main MCU? What are all the different ways Deadpool has died in the Marvel comics?