Merry Christmas! This month for the December 2025 episode of the RCEM Learning Podcast Andy and Dave are talking about higher MAP targets in sepsis and the routine use of antibiotics for max-fax fractures. Rob attempts a festive round up of the most impactful guidelines of the year. We'll then end with New Online. If you'd like to email us, please feel free to do so here. After listening, complete a short quiz to have your time accredited for CPD at the RCEMLearning website!

(03:19) New in EM - Higher MAP targets in Sepsis

• Efficacy of targeting high mean arterial pressure for older patients with septic shock (OPTPRESS): a multicentre, pragmatic, open-label, randomised controlled trial (Endo et al., 2025)

(15:19) Most Impactful Guidelines of the Year

• European Resucitation Guidelines - Guidelines on Cardiopulmonary Resuscitation (ERC, 2025)
• NHS England - Urgent and emergency care plan 2025/26 (NHS England, 2025)
• NHS England - Guidance to support the commissioning and delivery of ambulance services in 2025/26(NHS England, 2025)
• NICE - NG246 Overweight and obesity management (NICE, 2025)
• NICE - NG253 - Suspected sepsis in people aged 16 or over: recognition, assessment and early management (NICE, 2025)
• NICE - NG254 - Suspected sepsis in under 16s: recognition, diagnosis and early management (NICE, 2025)
• NICE - NG255 - Suspected sepsis in pregnant or recently pregnant people: recognition, diagnosis and early management (NICE, 2025)
• RCPCH - Facing the Future - standards for children and young people in emergency care settings (RCPCH, 2025)
• RCEM - GPEMS(RCEM, 2025)

(38:07) New in EM - Routine use of antibiotics in facial fractures

• Prophylactic antibiotic use in trauma patients with non-operative facial fractures: A prospective AAST multicenter trial (Mian et al., 2025)

(47:10) New Online – new articles on RCEMLearning for your CPD

• Is Normalisation of Deviance the "Standard" in Medicine? - Neel Bhandani
• Mental Illness in Children by Jidhin Davis
• Rest, sleep, and our breaks - the conversation we cant tire of - Amar Mashru