Decoding Healthcare Research

In this episode, join the conversation with Dr. E.F. Rain and Dr. Marta Rusek, a seasoned PhD Research Scientist at the Medical University of Lublin, Poland. With over 14 years of expertise in medical biology and biotechnology, Dr. Rusek specializes in the molecular mechanisms of Alzheimer's disease and connective tissue disorders. Discover how the ketogenic diet emerges as a potential alternative treatment for Alzheimer's and dementia. Dr. Rusek, also a Lecturer, shares insights gained from teaching Pathology, Physiology, Genetics, and Biochemistry to undergraduate Medical Sciences students. Don't miss this deep dive into medical science!

In this episode, join the conversation with Dr. E.F. Rain, Dr. Adrian Baranchuk, Professor of Medicine at Queen’s University, in Kingston, Canada, and Mario Bassi, a Medical Doctor candidate at the same institution. They delve into the sensitive and widely discussed topic of sudden cardiac arrests during sports events, specifically in soccer and basketball stadiums. The discussion revolves around the challenges associated with it and explores how deaths can be prevented by considering the conditions of the stadium and the event facility. Most importantly, they emphasize the significance of creating an effective chain of survival to promptly assist the person experiencing the attack with the proper equipment and trained personnel. From screening to pragmatic solutions, this episode raises awareness about an event that can impact anyone, not just athletes, at any moment. It goes beyond sports events and extends to individuals without previously detected conditions. Dr. Baranchuk is a member of numerous editorial boards (Europace, Annals of Noninvasive Electrocardiology, etc) and reviewer of several journals. He is currently the Editor-in-Chief of the Journal of Electrocardiology and JACC in Spanish.

In this episode join Dr. Riveros in the conversation with Dr. Dawn Bowdish, Associate Professor at McMaster and a Canada Research Chair in Aging & Immunity. They discuss the role of the gut microbiome and inflammation in health and disease, as well as the implications for how we age healthily. Dr. Bowdish started her lab at McMaster in 2009 where her team of post-doctoral fellows, undergraduate and graduate students study the process of macrophage phagocytosis, how macrophages influence the composition of the microbiome of the upper respiratory tract and how they recognize and destroy Streptococcus pneumoniae, the major cause of pneumonia in the elderly. She has won a number of early career awards including the Pfizer-ASPIRE award and the G. Jeannette Thorbecke Award from the Society of Leukocyte Biology. Her lab is funded by the CIHR, NSERC, the Labarge Optimal Aging Initiative and the Lung Association.

In this insightful episode, engage in a conversation with Dr. E.F. Rain and Dr. Victoria Vieira Potter, Associate Professor of Nutrition and Exercise Physiology at the University of Missouri, as they delve into the intricate aspects of menopause. Explore the crucial roles played by adipose tissue and estrogen in influencing metabolism, insulin sensitivity, and the array of symptoms associated with menopause. The discussion also encompasses practical measures women can adopt to alleviate menopausal symptoms and navigate this stage effectively. From exercise strategies to dietary considerations and insights into hormonal replacement, discover valuable approaches to enhance well-being during menopause. Dr. Vieira-Potter conducts primarily basic science studies, delving into mechanisms to prevent and treat obesity-related diseases. A major focus of her research revolves around understanding how exercise and estrogen influence adipose tissue metabolism, including the impact of estrogen loss on adipose tissue due to changes in physical activity behavior. In her work, she is actively forging collaborations with clinicians and scientists in the fields of neuroscience and psychiatry to further interrogate these questions, particularly in aging women.

In this episode, join the conversation with Dr. E.F. Rain and Dr. Woon Puay Koh. They discuss the benefits of daily consumption of coffee, black tea, or green tea and how it could actually be helping you age better. Dr. Koh is a Professor in the Healthy Longevity Translational Research Programme at Yong Loo Lin School of Medicine and a Joint-Professor at the Saw Swee Hock School of Public Health at the National University of Singapore. Prof. Koh is also a Senior Principal Investigator at the Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research (A*STAR), Singapore. She is the Principal Investigator of the Singapore Chinese Health Study, a cohort of 63,257 middle-aged and elderly Chinese Singaporeans established for the long-term study of dietary and environmental determinants of chronic diseases among Singaporeans. She has co-authored over 450 scientific papers on diet, lifestyle, and genes in relation to the risk of diseases such as cancer, cardiovascular diseases, diabetes, gout, osteoporosis, osteoarthritis, and aging outcomes.

In this episode, join the conversation with Dr. E.F. Rain and Dr. Janssen, an associate professor of internal medicine at Erasmus University Medical Center in Rotterdam, the Netherlands, and a researcher for more than 30 years on metabolic syndrome, insulin, growth hormone, and IGF-1. They discuss how the Westernization of diet and our general diet can contribute to the development of conditions such as metabolic syndrome, cancer, cardiovascular disease, and diabetes, among others. They also explore the possibility of preventing and correcting these issues through lifestyle changes.

In this episode join the conversation with Dr. E.F.Rain and Dr. Ian Greenlund, post-doctoral research fellow in cardiovascular medicine at Mayo Clinic in Dr. Virend Somers Laboratory. His research interests involve cardiovascular health, sleep physiology, sleep deprivation models, sex as a key biological variable, and neurovascular control of blood pressure, and autonomic control.

The conversation was based on the following article: 

Pabon E, Greenlund IM, Carter JR, de Wit H. Effects of alcohol on sleep and nocturnal heart rate: Relationships to intoxication and morning-after effects. Alcohol Clin Exp Res. 2022 Oct;46(10):1875-1887. doi: 10.1111/acer.14921. Epub 2022 Sep 1. PMID: 35953878; PMCID: PMC9826048.

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Disclosure: 

The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

Ketogenic diets have become increasingly popular due to their ability to produce rapid weight loss. These very low-carbohydrate diets put the body in a state of ketosis, altering physiology and metabolism. Ketogenic diets have been studied for weight loss, diabetes, performance enhancement, and as a treatment for refractory epilepsy, especially in children. However, the effects of ketogenic diets on many other health outcomes have been inconsistent between studies. While some systematic reviews have examined their impact in specific populations, a comprehensive assessment of the evidence from these existing reviews has been lacking.

In this episode, join Dr. E.F. Rain with Dr. Connie Jimenez, Ph.D., as they discuss vitamin C and its promising role in cancer treatment. Dr. Jimenez is the founder and head of the OncoProteomics Laboratory since 2006, as well as a Professor of 'Translational OncoProteomics' at the Department of Medical Oncology at the VU University Medical Center. She is a biologist with a keen interest in biomarker applications and protein signaling in cancer and neurodegenerative diseases. Her lab focuses on label-free mass spectrometry-based proteomics for candidate biomarker/target discovery and the development of innovative phosphoproteomics-based approaches for personalized medicine.

The conversation was based on the following article: 

Böttger F, Vallés-Martí A, Cahn L, Jimenez CR. High-dose intravenous vitamin C, a promising multi-targeting agent in the treatment of cancer. J Exp Clin Cancer Res. 2021 Oct 30;40(1):343. doi: 10.1186/s13046-021-02134-y. PMID: 34717701; PMCID: PMC8557029.

Follow us on social media!

-Instagram and TikTok: @agora_health 

-Facebook Page: Agora Health 

-Spotify, Apple Podcasts and Amazon Music: Decoding Healthcare Research 

- Dr.E.F.Rain as @dr.ef.rain on Instagram. 

Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

The foods we eat each day power our bodies, but can some types of foods increase our risk of serious diseases like cancer? A new comprehensive research review suggests the answer is yes when it comes to highly processed food products.

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-Reference:

Kliemann N, Al Nahas A, Vamos EP, Touvier M, Kesse-Guyot E, Gunter MJ, Millett C, Huybrechts I. Ultra-processed foods and cancer risk: from global food systems to individual exposures and mechanisms. British journal of cancer. 2022 Jul 1;127(1):14-20.