Vulvar lichen sclerosus sits at the intersection of dermatology and gynecology, making coordinated care essential. In this expert-led conversation, Dr. Charles Turck sits down with Dr. Christina Kraus and Dr. Jill Krapf to hear their perspectives on working through diagnostic and therapeutic challenges and approaching long-term care and surveillance across specialties. Dr. Kraus is a dermatologist at Kaiser Permanente in Southern California, and Dr. Krapf is an obstetrician-gynecologist and the Director of the Center for Vulvovaginal Disorders in Tampa, Florida.

Hand atopic dermatitis and other subtypes of chronic hand eczema can present similarly, but differences in their underlying drivers can have important implications for diagnosis and treatment. Review which clinical clues can point to hand atopic dermatitis, why underlying immune drivers matter, and how an accurate diagnosis can help support better long-term disease control with Dr. Shelina Ramnarine and Dr. Christopher Bunick, Associate Professor of Dermatology at Yale University School of Medicine in New Haven, Connecticut.

Inflammatory dermatoses don't always follow the rules. When clinical features overlap or presentations fall outside familiar patterns, reaching the right diagnosis requires a thoughtful, systematic approach. In this discussion with Dr. Alexandria May, Dr. Naiem Issa shares practical strategies for evaluating challenging cases and deciding when additional workup can help clarify the clinical picture. Dr. Issa is an Assistant Professor in the Dr. Philip Frost Department of Dermatology and Cutaneous Surgery at the University of Miami Miller School of Medicine, a Clinical Assistant Professor in the Department of Dermatology at the George Washington University School of Medicine and Health Sciences, and the Medical Director of Research and Academics at Forefront Dermatology in Vienna, Virginia.

Atopic dermatitis affecting the face, neck, hands, genital, and intertriginous areas can have a profound impact on patients' quality of life, even when overall disease involvement appears limited. Dr. Alexandria May sits down with Dr. Naiem Issa and Dr. Allison Truong as they share their perspectives on approaching treatment escalation, balancing efficacy with safety, and setting meaningful goals with patients. Dr. Issa is an Assistant Professor in the Dr. Philip Frost Department of Dermatology and Cutaneous Surgery at the University of Miami Miller School of Medicine, a Clinical Assistant Professor in the Department of Dermatology at the George Washington University School of Medicine and Health Sciences, and the Medical Director of Research and Academics at Forefront Dermatology in Vienna, Virginia. Dr. Truong is the Associate Division Chief of Dermatology at Cedars-Sinai Medical Group in Beverly Hills, California.

Advances in our understanding of itch biology are reshaping how we approach atopic dermatitis, with therapies targeting the interface between the immune and nervous systems becoming central in effectively alleviating itch. Join Dr. Brian Kim as he examines current treatment strategies, explains the continued importance of helping patients recognize and manage triggers and flares, and shares emerging approaches aimed at disrupting the bidirectional relationship between neural activity, itch, and inflammation. Dr. Kim is the Vice President and Chief Biotechnology Officer at Northwell Health and the Feinstein Institutes for Medical Research.

Pediatric atopic dermatitis is associated with a range of comorbidities, and it's important to understand how they intersect. That's why Dr. Lawrence Eichenfield joins us to explain how we should consider conditions like food allergy, asthma, anxiety and depression, urticaria, and alopecia areata in these patients. Dr. Eichenfield is a Distinguished Professor of Dermatology and Pediatrics at UC San Diego School of Medicine and Chief of Pediatric and Adolescent Dermatology at Rady Children's Hospital San Diego.

As targeted therapies for atopic dermatitis continue to advance, expectations for treatment success are evolving. Dr. Peter Lio, Clinical Assistant Professor of Dermatology and Pediatrics at Northwestern University Feinberg School of Medicine, explores how clinicians can look beyond incremental improvement toward more ambitious goals, including sustained itch control, clear or nearly clear skin, and a favorable safety profile.

Atopic dermatitis may look similar across patients, but could distinct underlying mechanisms call for more personalized treatment approaches? Dr. Peter Lio explores how emerging biomarkers could help us better understand individual disease drivers, guide treatment selection, and move individualized atopic dermatitis care closer to clinical practice. Dr. Lio is a Clinical Assistant Professor of Dermatology and Pediatrics at Northwestern University Feinberg School of Medicine.

Generalized pustular psoriasis (GPP) is a dermatologic emergency that can progress rapidly and lead to serious complications. Dr. Tina Bhutani joins us to explain why prompt recognition and treatment are critical for limiting potentially life-threatening consequences. Dr. Bhutani is an Associate Adjunct Professor of Dermatology at the University of California San Francisco School of Medicine and the owner of Synergy Dermatology.

Treatment success starts with understanding what matters to the patient, but in generalized pustular psoriasis (GPP), patient satisfaction alone may not be enough. Dr. Tina Bhutani joins us to share how she balances patients’ perspectives with the need for adequate disease control. She's an Associate Adjunct Professor of Dermatology at the University of California San Francisco School of Medicine and the owner of Synergy Dermatology.