What role does IL-36 signaling play in generalized pustular psoriasis (GPP) and why is it an emerging focus in neutrophilic inflammatory disease? Join Dr. Charles Turck and Dr. David Cotter, a dermatologist at Las Vegas Dermatology, as they explore the genetic and acquired mechanisms underlying IL-36 dysregulation, the pathways driving neutrophil recruitment and inflammation, and evolving evidence on IL-36 signaling in GPP and pyoderma gangrenosum.

For patients experiencing an acute flare of generalized pustular psoriasis (GPP), rapid recognition can make all the difference. Join Dr. Charles Turck and Dr. David Cotter, a dermatologist at Las Vegas Dermatology, as they discuss practical approaches for managing these flares and supporting patients throughout their care.

Generalized pustular psoriasis (GPP) can progress rapidly, making prompt and effective treatment essential. In this episode, Dr. Tina Bhutani discusses the evolution of GPP management and the key factors that guide treatment decisions, including the need for rapid disease control, patient safety, and comorbidity management. She's an Associate Adjunct Professor of Dermatology at the University of California San Francisco School of Medicine and the owner of Synergy Dermatology.

When it comes to psoriasis, what we see on the skin is only part of the story. Tune in to hear Dr. Amylynne Frankel, board-certified dermatologist at Advanced Dermatology and Cosmetic Surgery in Spartanburg, South Carolina, discuss why assessing quality of life, lesion location, and joint symptoms is essential for delivering truly patient-centered care.

From insurance delays to patient hesitancy, several obstacles can stand in the way of effective psoriasis treatment. Discover how education, communication, and close follow-up can help patients achieve better outcomes with Dr. Amylynne Frankel, board-certified dermatologist at Advanced Dermatology and Cosmetic Surgery in Spartanburg, South Carolina.

Although generalized pustular psoriasis (GPP) and plaque psoriasis are immunologically distinct diseases, they exist along a clinical spectrum with overlapping features and triggers. Find out more as Dr. Andrew Dorizas explores how patients may transition between disease states, reviews factors that can precipitate GPP-like flares, and discusses the importance of selecting targeted therapies based on the dominant disease presentation. Dr. Dorizas is a double board-certified dermatologist and Mohs surgeon affiliated with the University of Miami Health System and Advanced Dermatology of Alaska.

What clinical findings should prompt suspicion for generalized pustular psoriasis (GPP)? Find out as Dr. Shannon Trotter explores the evolving clinical presentation of GPP, from the often-overlooked pre-pustular phase to acute flares and post-flare disease. She also discusses the cutaneous and extracutaneous manifestations that can improve recognition, support accurate diagnosis, and help identify patients at risk for serious complications. Dr. Trotter is a board-certified dermatologist, Clinical Assistant Professor at Ohio University, and principal investigator for clinical trials at DOCS Dermatology Group in Ohio.

When we only view generalized pustular psoriasis (GPP) as an acute dermatologic emergency, we might miss opportunities for earlier recognition. Dr. Shannon Trotter, Clinical Assistant Professor at Ohio University and principal investigator for clinical trials at DOCS Dermatology Group in Ohio, joins us to examine the disease's full clinical spectrum, review common diagnostic pitfalls, and share practical insights for keeping GPP on the differential.

Generalized pustular psoriasis (GPP) extends beyond acute flares, with the chronic phase often carrying a significant physical, emotional, and psychosocial burden. In this episode, Dr. Shannon Trotter explores how individualized treatment strategies that account for patient goals, lifestyle, and fear of future flares can help support disease control and improve quality of life. Dr. Trotter is a Clinical Assistant Professor at Ohio University and principal investigator for clinical trials at DOCS Dermatology Group in Ohio.

In generalized pustular psoriasis (GPP) management, earlier recognition is just the beginning. Find out what's next for patient care as Dr. Shannon Trotter discusses clinical and research priorities that could reshape our approach, including expanding evidence for dual therapy in patients with coexisting plaque psoriasis and the evolving role of genetics in diagnosis and disease management. She's a Clinical Assistant Professor at Ohio University and principal investigator for clinical trials at DOCS Dermatology Group in Ohio.