This DermSurgery Digest bonus content aptly named “At the Microscope” shares the latest research and techniques in dermatopathology. In this episode, contributors will review the topic of perineural invasion in squamous cell carcinoma. Contributors to this podcast include Naomi Lawrence, MD, Dermatologic Surgery Digital Content Editor; Ashley Elsensohn, MD, MPH, DermSurgery Digest at the Microscope co-host; Christine Ahn, MD; Jeff Gardner, MD; Marina K. Ibraheim, MD; and Michael P. Lee, MD.

Articles featured in this episode include: 

•  Carter JB, Johnson MM, Chua TL, Karia PS, Schmults CD. Outcomes of primary cutaneous squamous cell carcinoma with perineural invasion: an 11-year cohort study. JAMA Dermatol. 2013 Jan;149(1):35-41. doi: 10.1001/jamadermatol.2013.746. PMID: 23324754 Link: https://pubmed.ncbi.nlm.nih.gov/23324754/
• Conde-Ferreirós A, Corchete LA, Jaka A, Santos-Briz Á, Fuente MJ, Posada R, Pons L, Podlipnik S, Pujol RM, Román-Curto C, Toll A, Cañueto J. Patterns of incidental perineural invasion and prognosis in cutaneous squamous cell carcinoma: A multicenter, retrospective cohort study. J Am Acad Dermatol. 2021 Jun;84(6):1708- 1712. doi: 10.1016/j.jaad.2020.08.017. Epub 2020 Aug 8. PMID: 32781186. Link: https://pubmed.ncbi.nlm.nih.gov/32781186/ 
• Harvey NT, Palmer DJ, Tucker P, Chakera A, Foster R, Lim W, Trevithick RW, Wood BA. Histological predictors of outcome for cutaneous squamous cell carcinoma in renal transplant patients: A case-control study. JAAD Int. 2023 Dec 29;15:51-58. doi: 10.1016/j.jdin.2023.11.010. PMID: 38371661; PMCID: PMC10869928. Link: https://pubmed.ncbi.nlm.nih.gov/38371661/ 
• Massey PR, Wang DM, Murad F, Mulvaney P, Moore K, Okhovat JP, Russell- Goldman E, Lin WM, Piris A, Huilgol SC, Ruiz ES, Schmults CD. Extensive Perineural Invasion vs Nerve Caliber to Assess Cutaneous Squamous Cell Carcinoma Prognosis. JAMA Dermatol. 2023 Dec 1;159(12):1332-1338. doi: 10.1001/jamadermatol.2023.3703. PMID: 37851425; PMCID: PMC10585586. Link: https://pubmed.ncbi.nlm.nih.gov/37851425/ 

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