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Diphenhydramine

- Trade – Benadryl
- Class – Antihistamine
- MOA – Antagonizes h1 histamine receptors
- Indication – Anaphylactic reaction
- Contraindication – Acute asthma as Benadryl thickens secretions.
- Side effects – Drowsiness, Dizziness, headache, excitable state, wheezing, thickening bronchial secretions, chest tightness, palpitations, hypotension, blurred vision, dry mouth, N/V, Diarrhea.
- Dosing
- Adult 25-50mg IV/IO/IM
- Pedi 2-12 years – 1-1.25 mg/kg IV/IO/IM
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By Michael Egan
Diphenhydramine

- Trade – Benadryl
- Class – Antihistamine
- MOA – Antagonizes h1 histamine receptors
- Indication – Anaphylactic reaction
- Contraindication – Acute asthma as Benadryl thickens secretions.
- Side effects – Drowsiness, Dizziness, headache, excitable state, wheezing, thickening bronchial secretions, chest tightness, palpitations, hypotension, blurred vision, dry mouth, N/V, Diarrhea.
- Dosing
- Adult 25-50mg IV/IO/IM
- Pedi 2-12 years – 1-1.25 mg/kg IV/IO/IM
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