Dr. Howard Smith Reports

Vidcast:  https://youtu.be/fMXBdLycA0w

The CPSC and Bombardier Recreational Products are recalling Ski-Doo Snowmobiles 2021-2022 Model Year.  The mufflers on these units may overheat leading to melting of the right-side vent grill, dripping molten plastic, and a fire hazard.  About 2400 snowmobiles were sold in the US and 3,000 were sold in Canada.  Stop using this vehicle immediately and contact a Ski-Doo dealer for a free repair.  More information from Bombadier US toll-free at 1-888-272-9222.

https://www.cpsc.gov/Recalls/2021/BRP-Recalls-Snowmobiles-Due-to-Fire-Hazard-Recall-Alert

#snowmobile #muffler #burn #fire #recall #skidoo

Vidcast:  https://youtu.be/fMXBdLycA0w

The CPSC and Bombardier Recreational Products are recalling Ski-Doo Snowmobiles 2021-2022 Model Year.  The mufflers on these units may overheat leading to melting of the right-side vent grill, dripping molten plastic, and a fire hazard.  About 2400 snowmobiles were sold in the US and 3,000 were sold in Canada.  Stop using this vehicle immediately and contact a Ski-Doo dealer for a free repair.  More information from Bombadier US toll-free at 1-888-272-9222.

https://www.cpsc.gov/Recalls/2021/BRP-Recalls-Snowmobiles-Due-to-Fire-Hazard-Recall-Alert

#snowmobile #muffler #burn #fire #recall #skidoo

Vidcast:  https://youtu.be/pNSzGnY-Pkw

The CPSC and Leisure Time Products now recall Backyard Discovery Big Brutus, Little Brutus and Mini Brutus Metal Swing Sets. The swing hanger attachment ism defective and the swing may disconnect from the top tube leading to a child falling and sustaining an injury.  About 9,000 of these swings were sold in the US and 270 were sold in Canada online at Amazon.com, backyarddiscovery.com, Homedepot.com, Lowes.com Wayfair.com, among others.  Stop using these swings and contact Leisure Time Products at 1-800-856-4445 or online at backyarddiscovery.com to receive a free repair kit.

https://www.cpsc.gov/Recalls/2021/Leisure-Time-Products-Recalls-Brutus-Swing-Sets-Due-to-Injury-Hazard-Recall-Alert

#swing #defectiveattachment #falls #recall

Vidcast:  https://youtu.be/pNSzGnY-Pkw

The CPSC and Leisure Time Products now recall Backyard Discovery Big Brutus, Little Brutus and Mini Brutus Metal Swing Sets. The swing hanger attachment ism defective and the swing may disconnect from the top tube leading to a child falling and sustaining an injury.  About 9,000 of these swings were sold in the US and 270 were sold in Canada online at Amazon.com, backyarddiscovery.com, Homedepot.com, Lowes.com Wayfair.com, among others.  Stop using these swings and contact Leisure Time Products at 1-800-856-4445 or online at backyarddiscovery.com to receive a free repair kit.

https://www.cpsc.gov/Recalls/2021/Leisure-Time-Products-Recalls-Brutus-Swing-Sets-Due-to-Injury-Hazard-Recall-Alert

#swing #defectiveattachment #falls #recall

Vidcast:  https://youtu.be/MHMadmBr0q8

Today’s medical discoveries that point to future therapy.

New developments for:  

4D Printing Spinal Scaffolds

Ultrasound Neuromodulation

Needle-Free Blood Glucose Testing s

Electrical Glue For Blood Vessels

Micro Ultrasound

Speedy Wound Healing

All this on  Medicine of the Future.

Spinal fusion is a common procedure, but when a bone autograft is unavailable or fails, an artificial scaffold is needed.  Enter 4D printing using collagen-hydroxyapatite ink that permits natural bony ingrowth and vascularization.  A South Korean team is perfecting this process that not may not only work with bone but also with other tubular structures including muscle, tendons, and nerve.  By the way, what’s the 4th dimension after width, length, and height.  It’s TIME as the 3D printed prosthesis evolves with the entry of living cells.

A key to treatment of neurologic disorders including Parkinson’s is neuromodulation, the precise delivery of a stimulus to affected nerves using electricity, magnetism, and pharmaceuticals.  Researchers at Pittsburgh’s Carnegie-Mellon University now add focused ultrasound to these other modalities.  This non-invasive technique targets and selectively but reversibly transforms cell subpopulations more effectively than the other methods.  It may also have broad applications for treatment of many neuropsychiatric disorders.

Determining blood glucose without needles is closer to reality with the report from UC-San Diego announcing development of a skin sensor capable of measuring the sugar content of sweat.  An individualized calculation then accurately determines a person’s blood sugar level with 95% accuracy. A large-scale study is still ahead, but this technique could provide continuous glucose monitoring with only monthly pinpricks for recalibration.

Patching blood vessels without surgery may now be possible with an electrically-activated bioadhesive or glue developed in Singapore by nanobiologists and perfected with the help of MIT and Harvard scientists.  The aptly-named Voltaglue patch is delivered to the damaged blood vessel zone via a balloon catheter and then activated in minutes by a micro-current.  Voltaglue would also work to patch other tissue tears without open surgery.

A hair-thin ultrasound probe can be introduced via catheters into blood vessels and body cavities to examine and study human disease at the cellular level.  Developed at the UK’s University of Nottingham, this phonon probe technique permits clinicians to study living cells at a magnification level conventionally only possible under a microscope with fixed cells on a slide.

Wound healing is often slow.  Now Mayo Clinic researchers have discovered a platelet-derived purified exosomal product, PEP for short, that turbocharges the healing process of wounds that develop due to an insufficient blood supply.  This compound promises to revolutionize healing in diabetics, heart attack victims, those with peripheral arterial disease, trauma victims, and those und

Vidcast:  https://youtu.be/MHMadmBr0q8

Today’s medical discoveries that point to future therapy.

New developments for:  

4D Printing Spinal Scaffolds

Ultrasound Neuromodulation

Needle-Free Blood Glucose Testing s

Electrical Glue For Blood Vessels

Micro Ultrasound

Speedy Wound Healing

All this on  Medicine of the Future.

Spinal fusion is a common procedure, but when a bone autograft is unavailable or fails, an artificial scaffold is needed.  Enter 4D printing using collagen-hydroxyapatite ink that permits natural bony ingrowth and vascularization.  A South Korean team is perfecting this process that not may not only work with bone but also with other tubular structures including muscle, tendons, and nerve.  By the way, what’s the 4th dimension after width, length, and height.  It’s TIME as the 3D printed prosthesis evolves with the entry of living cells.

A key to treatment of neurologic disorders including Parkinson’s is neuromodulation, the precise delivery of a stimulus to affected nerves using electricity, magnetism, and pharmaceuticals.  Researchers at Pittsburgh’s Carnegie-Mellon University now add focused ultrasound to these other modalities.  This non-invasive technique targets and selectively but reversibly transforms cell subpopulations more effectively than the other methods.  It may also have broad applications for treatment of many neuropsychiatric disorders.

Determining blood glucose without needles is closer to reality with the report from UC-San Diego announcing development of a skin sensor capable of measuring the sugar content of sweat.  An individualized calculation then accurately determines a person’s blood sugar level with 95% accuracy. A large-scale study is still ahead, but this technique could provide continuous glucose monitoring with only monthly pinpricks for recalibration.

Patching blood vessels without surgery may now be possible with an electrically-activated bioadhesive or glue developed in Singapore by nanobiologists and perfected with the help of MIT and Harvard scientists.  The aptly-named Voltaglue patch is delivered to the damaged blood vessel zone via a balloon catheter and then activated in minutes by a micro-current.  Voltaglue would also work to patch other tissue tears without open surgery.

A hair-thin ultrasound probe can be introduced via catheters into blood vessels and body cavities to examine and study human disease at the cellular level.  Developed at the UK’s University of Nottingham, this phonon probe technique permits clinicians to study living cells at a magnification level conventionally only possible under a microscope with fixed cells on a slide.

Wound healing is often slow.  Now Mayo Clinic researchers have discovered a platelet-derived purified exosomal product, PEP for short, that turbocharges the healing process of wounds that develop due to an insufficient blood supply.  This compound promises to revolutionize healing in diabetics, heart attack victims, those with peripheral arterial disease, trauma victims, and those undergoing radiation therapy.  The best news: PEP triggers development of normal rather than scar tissue.

These and other cutting edge solutions are coming to your doctor’s office and our hospitals…….some day soon!

https://aip.scitation.org/doi/10.1063/5.0035601

https://www.nature.com/articles/s41467-021-22743-7

https://advances.sciencemag.org/content/7/14/eabf6855

https://pubs.acs.org/doi/10.1021/acssensors.1c00139#

https://www.nature.com/articles/s41377-021-00532-7

https://www.sciencedaily.com/releases/2021/04/210428132936.htm

#4dprinting #bone #spinalfusion #ultrasound #neurology #psychiatry #glucose #diabetes #sweat #voltaglue #vesseltears #bioadhesives #pathology #biopsy #histology #pep #healing #diabetes #atherosclerosis #radiation #trauma

4dprinting, bone, spinalfusion, ultrasound, neurology, psychiatry, glucose, diabetes, sweat, voltaglue, vesseltears, radiation, trauma

Vidcast:  https://youtu.be/R2F2OSytgGI

A new nanoparticle-based vaccine stimulates protective antibodies to the British, South African, and Brazilian variants in addition to the original Chinese CoVid.  Immunologists from San Diego’s Scripps Research Institute and Philadelphia’s Temple University now describe it on the pre-publication server biorixiv.org.

Their vaccine is a highly immunogenic version of mutated CoVid spike protein attached to nanoparticles.   Testing in mice shows it induces high titers of protective antibody because the nanoparticles assure the continued persistence of CoVid antigen in the lymph node factories that manufacture protective antibodies.

This technology can lead the way to more powerful vaccines that finally squelch CoVid and prevent its mutation to ever more dangerous variants.

https://www.biorxiv.org/content/10.1101/2021.03.26.437274v2.full.pdf+html

#CoVid #vaccine #nanoparticle #variants

Vidcast:  https://youtu.be/R2F2OSytgGI

A new nanoparticle-based vaccine stimulates protective antibodies to the British, South African, and Brazilian variants in addition to the original Chinese CoVid.  Immunologists from San Diego’s Scripps Research Institute and Philadelphia’s Temple University now describe it on the pre-publication server biorixiv.org.

Their vaccine is a highly immunogenic version of mutated CoVid spike protein attached to nanoparticles.   Testing in mice shows it induces high titers of protective antibody because the nanoparticles assure the continued persistence of CoVid antigen in the lymph node factories that manufacture protective antibodies.

This technology can lead the way to more powerful vaccines that finally squelch CoVid and prevent its mutation to ever more dangerous variants.

https://www.biorxiv.org/content/10.1101/2021.03.26.437274v2.full.pdf+html

#CoVid #vaccine #nanoparticle #variants

Vidcast:  https://youtu.be/zOJBaUruPCY

Young women consuming more than two servings a day of sugar-sweetened drinks more than double their risk (2.2) of bowel cancer.  Public health researchers at St. Louis’ Washington University issue this warning after comparing the dietary records of 95,464 women participating in the Nurses’ Health Study.

The cancer risk escalates 16% for every extra sugary drink serving/day.  That risk doubles to 32% for those consuming an extra beverage during their teen years.   Conversely, eliminating that sugary drink in favor of coffee, milk, or diet drinks reduces the colon cancer risk from 17-36%.

Your bowels may not tolerate sugar well, but colon cancer feeds off it.

https://gut.bmj.com/content/early/2021/05/09/gutjnl-2020-323450

#cancer #sugar #softdrinks #colon

Vidcast:  https://youtu.be/zOJBaUruPCY

Young women consuming more than two servings a day of sugar-sweetened drinks more than double their risk (2.2) of bowel cancer.  Public health researchers at St. Louis’ Washington University issue this warning after comparing the dietary records of 95,464 women participating in the Nurses’ Health Study.

The cancer risk escalates 16% for every extra sugary drink serving/day.  That risk doubles to 32% for those consuming an extra beverage during their teen years.   Conversely, eliminating that sugary drink in favor of coffee, milk, or diet drinks reduces the colon cancer risk from 17-36%.

Your bowels may not tolerate sugar well, but colon cancer feeds off it.

https://gut.bmj.com/content/early/2021/05/09/gutjnl-2020-323450

#cancer #sugar #softdrinks #colon