Vidcast: https://youtu.be/2MytwFMumnw
Today’s medical discoveries that point to future therapy.
New developments for:
Nanoparticle Antibacterials, Radical Prostatectomy, Preventing Abdominal Aortic, Aneurysms, Glioblastoma, Nanorobots
All this on Medicine of the Future.
Bacteria are getting smarter and more resistant to all known antibiotics, and many of them resist treatment by hiding in cells where antibiotics cannot penetrate. Swiss bioengineers have developed bacterial-toxic cerium oxide nanoparticles that do get inside cells and their components. They successfully tested these nanoparticles against MRSA, the highly resistant version of staph aureus.
Physiologists and urologists at New York’s Albert Einstein College of Medicine discovered a small interfering RNA molecule that promotes nerve regeneration when packaged in gel nanoparticles and sprayed on tissues. The researchers successfully tested this siRNA-gel compound in a mouse model with damaged erectile nerves by applying the agent immediately following nerve damage. This therapy may not only prevent the devastating downside to radical prostatectomy but may also help recovery of spinal cord injury victims.
Abdominal aortic aneurysms that grow progressively and burst in a deadly, bloody tsunami cannot be stopped with current therapy. Now University of Michigan surgeons identify a gene that is turned on in those suffering from these potentially fatal aneurysms. They successfully stopped the formation and progression of abdominal aortic aneurysms in afflicted mice by blocking this gene’s function. Hopefully, this same genetic engineering will work in humans.
The brain glioblastoma that killed Senators Ted Kennedy and John McCain is the most aggressive from of brain cancer and fewer than 7% survive. University of Minnesota neurosurgeons, analyzing those few lucky patients to discover their body’s survival secrets, find that their immune cells resisted recruitment and shut down by their tumors. This process is mediated by a protein PI3K. The investigators went further and now show that drugs targeting PI3K prolong survival in an animal brain cancer model. Hopefully such drugs or gene therapy to block PI3K production will work in humans.
These and other cutting edge solutions are coming to your doctor’s office and our hospitals…….some day soon!
https://pubs.rsc.org/en/content/articlelanding/2021/NR/D0NR08285F#!divAbstract
https://insight.jci.org/articles/view/138484
https://rupress.org/jem/article-abstract/218/6/e20201839/211922/Inhibition-of-macrophage-histone-demethylase-JMJD3?redirectedFrom=fulltext
https://www.pnas.org/content/118/16/e2009290118