Vidcast: https://youtu.be/_HW1iHftI3o
New developments for:
Skin Cancer, Pancreatic Cancer, Stroke, Pediatric Heart Disease, Male Contraception, Genetic Engineering
All this on Medicine of the Future.
Researchers at the Ohio State Comprehensive Cancer Center suggest that the already available and inexpensive neurodrug dopamine can reduce the development of common skin cancers including basal cell and squamous cell carcinomas. Testing this drug in mice, it stimulates receptors in the cell that block the cancer-inducing effects of ultraviolet light. The drug could be a godsend for those with light-complexions and a propensity for skin cancer
University of Pennsylvania oncologists report a preliminary phase 1 study of a drug that drives killer T cells into notoriously treatment-resistant pancreatic cancer. The drug selicrelumab was given to 15 patients before their surgery and chemotherapy. The excised tumor specimens were T-cell enriched and less fibrotic permitting better penetration of other therapeutic agents. The treated group lived nearly twice as long.
mRNA delivered to brain tissues can induce an agent that protects during a stroke. Tokyo neuroscientists and bioengineers developed mRNA in a polymer nanoball that codes for BDNF, brain-derived neurotrophic factor, that enhances the survival of neurons deprived of oxygen during a stroke. The best news is that the mRNA treatment works well even if given 2 to 5 days after the neuro-catastrophic stroke.
University of Minnesota bioengineers have created pediatric heart valve replacements that can grow with their young recipients. The researchers constructed valved conduits made from fibroblast-derived collagen that grew with the recipient lambs. These valves revealed good function up to a year after implantation and developed less calcification than conventional bioprosthetic valves.
A Chinese herbal compound, triptonide, given orally can reduce sperm motility producing consistent yet reversible male infertility after 6 weeks of therapy. Collaborators at the University of Nevada and UCLA developed and tested this compound which may well be the first practical non-hormonal male contraceptive. Triptonide blocks the last steps of sperm assembly and may be purified from the Chinese herb or directly synthesized.
Wearable technology is on the rise, and many smart sensors may require wearable antennas to transmit that data for processing. Such antennas must be able to twist, compress, and stretch. Bioengineers at Penn State in collaboration with China’s Hebei University of Technology have now developed a layered copper mesh antenna with transmission properties minimally affected by geometric changes.
Genetic engineering, the ability to treat diseases by modifying a human’s cellular genetic makeup takes two giant steps forward. First…….Geneticists at UC-San Francisco announce a modification to the epic CRISPR-CAS genetic editing technique that permits controlling expression of given genes without modifying the core cellular DNA. This technique, called CRISPRoff, can modify epigenetic material in