Dr RR Baliga's "Got Knowledge Doc" Podkast

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🧬 Middle-age spread decoded!

🕰️ Visceral fat grows in midlife not from bigger cells—but new ones!

🎯 CP-A cells fire up fat formation via LIFR–STAT3 🔥

💊 Targeting them may halt metabolic disease before it starts.

#Aging #Obesity #CellBiology #Metabolism 🧫

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🚨 New era in heart disease prediction!

🧬 + 🧪 + 🤖 = Meta-prediction model that beats PCE & QRISK3

📈 Detects hidden CAD risk in young, women & "low-risk" groups

🎯 Precision prevention just got personal.

🫀 Published in Nature Medicine

#CardioTwitter #AI #Genomics #CAD

Epicurus (341–270 BC) was an ancient Greek philosopher who founded Epicureanism, emphasizing the pursuit of a tranquil, happy life through ataraxia (freedom from fear) and aponia (absence of pain).

His teachings combined atomism, ethics, and naturalistic theology, advocating simple living, friendship, and the rejection of superstition.

🚨ECLIPSE Trial Results🚨

Orbital atherectomy 🌀 vs. balloon angioplasty 🎈 before stenting in severe coronary calcification 💔

🎯 No added benefit with atherectomy

🧠 Balloon-first + imaging = smart strategy

📊 Lancet 2025 | #CardioTwitter #InterventionalCardiology #ECLIPSETrial

"Your DNA 🧬 is just half the story — your exposome 🌍 writes the rest! From air 🌫️ to food 🍎 to stress 😰, exposomics unlocks the hidden drivers of health 🔍💥.

Predict. Prevent. Prosper. 🚀

#Exposomics #PrecisionMedicine"

🫀💊 Scientists found a way to trick heart cells into calming down! Blocking stiffness signals with a smart drug combo reduced scarring and helped hearts pump better in mice.

A big step toward #mechanotherapy! 🧠🔬🐭 #CardioTwitter #Fibrosis #HeartHealth

🧪 Routine scans after cancer treatment: lifesaver or false security?

😰 Evidence shows no survival benefit, but lots of scanxiety, cost, and early toxicity.

💡 Sometimes, less is more. Ask why before you scan. #CancerSurveillance #Oncology 🩺📉

⏰🫀 Your heart heals differently depending on the time of day!

A protein duo—BMAL1 + HIF2α—peaks in the afternoon, boosting AREG, a heart repair helper.

💔 Morning heart attacks? Worse outcomes.

🕒 Timing meds = better healing.

#Chronotherapy #HeartHealth #CircadianScience

🧬💉 Bitten 200+ times, one man's blood helped create a universal antivenom! 🦸‍♂️🐍

Human antibodies + varespladib = protection from 19 deadly snake venoms 🛡️🔥

Science just took a big bite out of snakebite! 🌍🔬 #Snakebite #Antivenom #Innovation

🏃‍♂️ Cardiac arrests in marathons stable, but deaths cut in half!

🫀 CAD now the top cause, not HCM.

🚑 Quick CPR + AED saves lives.

📈 Poisson stats confirm the trends!

#Running #HeartHealth #MarathonMedicine