The search for Nancy Guthrie, the missing mother of Today show co-host Savannah Guthrie, is entering a critical new phase as troubling new details emerge about blood evidence inside the home where she disappeared. In this episode of Drop Dead Serious, Ashleigh Banfield reveals new information about blood discovered inside the home and what it could mean for the investigation. Ashleigh is joined by renowned investigative genetic genealogist CeCe Moore, the chief genetic genealogist at Parabon NanoLabs, whose work using DNA and family-tree analysis has helped identify suspects and victims in hundreds of criminal cases. If you have any information, call 1-800-CALL-FBI

Three weeks into the disappearance of Nancy Guthrie, the 84-year-old mother of Today show co-host Savannah Guthrie, the investigation in Tucson’s Catalina Foothills has grown more intense and more complex. What began as a missing persons case on February 1 quickly shifted into a criminal investigation after her purse, phone, wallet, and vehicle were found inside her home and blood was discovered near the front entrance. In this episode of Drop Dead Serious, Ashleigh Banfield walks through the full timeline of the Nancy Guthrie mystery, including the Nest doorbell footage of a masked suspect with an Ozark Trail backpack, the unknown male DNA recovered from gloves found near the property, and the controversy surrounding evidence sent to a private Florida lab. We also examine the escalating ransom demands that led to a federal arrest, the FBI’s use of BlueFly signal detection technology to search for Nancy’s pacemaker, and the ongoing questions about motive, suspects, and whether this was a targeted kidnapping. With more than 20,000 tips reviewed and over $200,000 in reward money offered, this Nancy Guthrie missing update breaks down every major twist and where the case stands right now. If you have information, contact: 1-800-CALL-FBI

After days of speculation about whether the 84-year-old mother of Today show co-host Savannah Guthrie could have been taken across the U.S.–Mexico border, Mexican authorities are now publicly responding, and they are pushing back hard.
With Sheriff Chris Nanos saying hundreds of personnel are reviewing thousands of leads and investigators not ruling out a possible accomplice tied to the suspected kidnapper seen on surveillance video, the question remains: what is really happening behind the scenes on Day 19 of the search for Nancy Guthrie? In this episode of Drop Dead Serious, Ashleigh Banfield breaks down every new development in the Nancy Guthrie case.

Is the FBI now looking south of the border? Law enforcement sources tell multiple outlets that the FBI has contacted Mexican authorities in connection with the disappearance of Nancy Guthrie, even though Sheriff Chris Nanos has repeatedly stated there is no evidence she was taken to Mexico. In this episode of Drop Dead Serious, Ashleigh Banfield breaks down the conflicting statements about Mexico and dives into the truth about eerie Google searches tied to the Nancy Guthrie mystery, including records showing searches for Nancy’s address, Google image lookups of her home, and even searches for Savannah Guthrie’s salary in the days and months leading up to her disappearance.

Pima County Sheriff Chris Nanos is now explicitly clearing the entire Guthrie family, including all siblings and spouses. That statement comes less than 24 hours after previous interviews where he said no one had been cleared. Meanwhile, federal agents have reportedly shown up at gun stores across Tucson with 40 names and 40 photos, asking employees if any of those individuals purchased weapons. In this episode of Drop Dead Serious, Ashleigh Banfield is joined by former Special Deputy U.S. Marshal and CEO of Coursen Security Group, Spencer Coursen, to break down all the latest updates and where this investigation is heading next.

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We are now on Day 13 in the search for Nancy Guthrie, and there have been explosive new developments. In this episode of Drop Dead Serious, Ashleigh Banfield breaks down the breaking developments after SWAT was deployed roughly two miles from Nancy’s home and three people were detained as part of an active law enforcement operation. This comes as the investigation into Nancy Guthrie’s disappearance continues to intensify, with federal and local agencies working around the clock.